Native Human Coagulation Factor IX

• Cat.No.: F9-671H
• Product Overview: NativeHuman F9 is prepared from fresh frozen plasma by a combination ofconventional procedures and immunoaffinity chromatography.

Specification

• Cat. No.: F9-671H
• Description: Human F9, activated by either the Contact or Tissue FactorPathway, is esponsible for the activation of Factor X to Xa.
• Source: Human Plasma
• Form: Frozenliquid in 0.02 M Tris-HCl Buffer + 0.1 M NaCl + 0.001 M Benzamidine, pH 7.4.
• BiologicalActivity: Activity isdetermined via clotting assay.
• Endotoxin Level: < 0.1 ng/ug ofprotein.
• Concentration: 5.0 mg/ml
• Molecular Weight: 56 kDa
• Storage: Store at -80°C. Stable for 3 years fromdelivery. Avoid repeated freeze-thaw cycles.
• Pathways: Blood Clotting Cascade; Complement andCoaqulation Cascades; Extrinsic Pathway; Formation of Fibrin Clot (ClottingCascade); Gamma-carboxylation of protein precursors; Gamma-carboxylation,transport, and amino-terminal cleavage of proteins; Hemostasis; IntrinsicPathway; Metabolism of proteins; Post-translational protein modification;Removal of aminoterminal propeptides from gamma-carboxylation proteins

Gene Information

• Gene Name: F9 coagulation factor IX [ Homo sapiens]
• Official Symbol: F9
• Synonyms: F9; coagulation factor IX;FIX;P19; PTC; HEMB; MGC129641; MGC129642; F9p22; factor9; factor IX F9; serine protease; Christmas factor; OTTHUMP00000024154;plasma thromboplastic component; EC 3.4.21.22; EC 3.4.21; Coagulation factorIX; Plasma thromboplastic component; Coagulation factor IX light chain; Coagulationfactor IX heavy chain; Factor IX; hemophilia B
• Gene ID: 2158
• mRNA Refseq: NM_000133
• Protein Refseq: NP_000124
• MIM: 300746
• UniProt ID: P00740
• Chromosome Location: Xq27.1-q27.2
• Function: peptidase activity; calciumion binding; serine-typeendopeptidase activity