Active Recombinant Human DEFB4A protein

• Cat.No.: DEFB4A-5192H
• Product Overview: Recombinant Human DEFB4A, a single, non-glycosylated polypeptide chain containing 50 amino acids was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Form: Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB, pH 7.4 + 130 mM NaCl.
• Bio-activity: Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 100 ng/ml.Specific Activity: ＞1.0 × 10^4 IU/mg.
• Molecular Mass: 6.0 kDa
• Protein length: 50 amino acids
• Endotoxin: Less than 1EU/μg as determined by LAL method.
• Purity: >98% by HPLC and SDS-PAGE
• Storage: This lyophilized preparation is stable at 2-4 centigrade, but should be kept desiccated at -20 centigrade for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4 centigrade. For maximal stability, apportion the reco
• Reconstitution: Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions.

Gene Information

• Gene Name: DEFB4A defensin, beta 4A [ Homo sapiens ]
• Official Symbol: DEFB4A
• Synonyms: DEFB4A; defensin, beta 4A; DEFB2, DEFB4, DEFB102, defensin, beta 2 , defensin, beta 4; beta-defensin 4A; DEFB 2; HBD 2; SAP1; defensin, beta 2; defensin, beta 4; skin-antimicrobial peptide 1; BD-2; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102
• Gene ID: 1673
• mRNA Refseq: NM_004942
• Protein Refseq: NP_004933
• MIM: 602215
• UniProt ID: O15263
• Chromosome Location: 8p23.1
• Pathway: Beta defensins, organism-specific biosystem; Defensins, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem