Recombinant Rhesus CSF2 protein
Cat.No. : | CSF2-360R |
Product Overview : | Recombinant Rhesus CSF2 protein was expressed in Escherichia coli. |
- Specification
- Gene Information
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Description : | Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is secreted by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimulation. It was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors and has functions of stimulates the growth and differentiation of hematopoietic precursor cells from various lineages. GM-CSF has also been reported to have a functional role on non-hematopoietic cells and can induce human endothelial cells to migrate and proliferate. Additionally, it can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. It is reported that GM-CSF has no biological effects across species. |
Source : | E.coli |
Species : | Rhesus |
Form : | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4. |
Bio-activity : | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 × 10⁷ IU/mg. |
Molecular Mass : | Approximately 14.4 kDa, a single non-glycosylated polypeptide chain containing 127 amino acids. |
Protein length : | 127 |
AA Sequence : | APARSPSPGTQPWEHVNAIQEARRL LNLSRDTAAEMNKTVEVVSEMFDLQ EPSCLQTRLELYKQGLQGSLTKLKG PLTMMASHYKQHCPPTPETSCATQI ITFQSFKENLKDFLLVIPFDCWEPV QE |
Endotoxin : | Less than 1 EU/μg of rRhGM-CSF as determined by LAL method. |
Purity : | >98% by SDS-PAGE and HPLC analysis. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions. |
Gene Name : | CSF2 |
Official Symbol : | CSF2 |
Synonyms : | Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α |
Gene ID : | 574371 |
mRNA Refseq : | NM_001032949.2 |
Protein Refseq : | NP_001028121.1 |
UniProt ID : | Q9GL44 |
Products Types
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◆ Lysates | ||
CSF2-1008MCL | Recombinant Mouse CSF2 cell lysate | +Inquiry |
CSF2-740RCL | Recombinant Rat CSF2 cell lysate | +Inquiry |
CSF2-3008HCL | Recombinant Human CSF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionThe sequence of CSF2 is moderately conserved across different species.
The length of CSF2 protein varies but is typically around 144 amino acids.
The primary function of CSF2 is to regulate the production and differentiation of white blood cells.
CSF2 is often expressed in immune cells, specifically in macrophages, T cells, and endothelial cells.
CSF2 stands for Colony Stimulating Factor 2.
CSF2 dysregulation has been linked to autoimmune diseases and inflammatory disorders.
CSF2 is involved in the stimulation of stem cells to produce granulocytes and monocytes.
Customer Reviews (3)
Write a reviewThe product's adherence to regulatory standards aligned with our lab's commitment to responsible and transparent research.
The manufacturer's commitment to meeting regulatory requirements demonstrated its dedication to ethical research practices.
Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.
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