Recombinant Human Protein Tyrosine Phosphatase, Non-Receptor Type 9
Cat.No. : | PTPN9-1910H |
Product Overview : | Recombinant humanPTPN9 is expressed in E. coli; it contains the catalytic domain of PTPN9(residues 285-593) and has a molecular weight of 34.3 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PTPN9-1910H |
Description : | PTPN9 (proteintyrosine phosphatase from megakaryocyte-2) was originally cloned from humanMEG-01 megakaryocyte and umbilical vein endothelial cell cDNA. The catalyticdomain is located at the carboxy-terminus of the full-length protein and ithas 30-40% sequence identity to other known protein tyrosine phosphatases.The full-length enzyme has been reported to bind phospholipid with highaffinity and that this binding is important for MEG2 activity on secretoryvesicles. |
Source : | E. coli |
Species : | Human |
Form : | 25 mM Tris-HCl (pH8.0), 75 mM NaCl, 0.05% Tween-20, 2 mM EDTA, 1 mM DTT and 50% glycerol.Liquid at -20°C. |
Purity : | Greater than 95% asdetermined by Coomassie-stained SDS-PAGE gel. |
Specific Activity : | 3.5 U/μg. One unitwill hydrolyze 1 nmol of p-nitrophenyl phosphate per minute at pH 7.4 and30°C. Assay buffer: 50 mM HEPES (pH 7.4), 2 mM EDTA, 3 mM DTT, 100 mM NaCland 50 mM pNPP. |
Applications : | Removal ofphosphates from target substrates. Useful for the study of enzyme kinetics,regulation and for inhibitors screening. |
Storage : | 6 months at -20°C. |
Gene Name : | PTPN9 protein tyrosinephosphatase, non-receptor type 9 [ Homo sapiens ] |
Official Symbol : | PTPN9 |
Synonyms : | PTPN9; proteintyrosine phosphatase, non-receptor type 9; MEG2; PTPMEG2; tyrosine-proteinphosphatase non-receptor type 9; PTPase MEG2; PTPase-MEG2; OTTHUMP00000183522;protein-tyrosine phosphatase MEG2 |
Gene ID : | 5780 |
mRNA Refseq : | NM_002833 |
Protein Refseq : | NP_002824 |
MIM : | 600768 |
UniProt ID : | P43378 |
Chromosome Location : | 15q23 |
Function : | hydrolase activity;non-membrane spanning protein tyrosine phosphatase activity; protein binding;protein tyrosine phosphatase activity |
Products Types
◆ Recombinant Protein | ||
PTPN9-4496R | Recombinant Rat PTPN9 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPN9-1300H | Recombinant Human PTPN9 protein(Ala285-Gln593), His&GST-tagged | +Inquiry |
PTPN9-7283M | Recombinant Mouse PTPN9 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPN9-5540C | Recombinant Chicken PTPN9 | +Inquiry |
PTPN9-6099H | Recombinant Human PTPN9 Protein (Gln289-Gln593), N-His tagged | +Inquiry |
◆ Lysates | ||
PTPN9-518HCL | Recombinant Human PTPN9 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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