Recombinant Human Vascular Endothelial Growth Factor A
Cat.No. : | VEGFA-5532H |
Product Overview : | Recombinant human VEGF189,a 21 kDa protein consisting of 189 amino acid residues, is produced as ahomodimer. |
- Specification
- Gene Information
- Related Products
Cat. No. : | VEGFA-5532H |
Description : | This gene is amember of the platelet-derived growth factor (PDGF)/vascular endothelialgrowth factor (VEGF) family and encodes a protein that is often found as adisulfide linked homodimer. This protein is a glycosylated mitogen thatspecifically acts on endothelial cells and has various effects. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized |
Purity : | > 98% asdetermined by SDS-PAGE analysis and visualised by silver stain. |
Molecular Mass : | 42 kDa |
Endotoxin Level : | < 0.1 ng/μg ofVEGF189 |
Biological Activity : | Determined by thestimulation of 3H-thymidine incorporation and cell proliferation by humanumbilical vein endothelial cells for VEGF189. The ED50 is in therange of 1-2 ng/ml. |
Reconstitution : | Centrifuge vialprior to opening. First add sterile distilled water to the vial to fullysolubilize the protein to a concentration not less than 0.1-1.0 mg/ml. Aftercomplete solubilization of the protein, it can be further diluted to otheraqueous solutions. |
Storage : | Store lyophilizedprotein at -20°C to -80°C and reconstituted protein in working aliquots at-20°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | VEGFA |
Pathways : | Bladder cancer;Cytokine-cytokine receptor interaction; Endochondral Ossification; Focaladhesion; Glypican 1 network; HIF-1-alpha transcription factor network;HIF-2-alpha transcription factor network; Heart Development; Hemostasis;Hypertrophy Model; Id Signaling Pathway; Integrins in angiogenesis;Neurophilin interactions with VEGF and VEGFR; Pancreatic cancer; Pathways incancer |
Gene Name : | VEGFA vascular endothelialgrowth factor A [ Homo sapiens ] |
Synonyms : | VEGFA;vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascularendothelial growth factor A; OTTHUMP00000016487; OTTHUMP00000016488;OTTHUMP00000165985; OTTHUMP00000165986; OTTHUMP00000165987;OTTHUMP00000224107; OTTHUMP00000224108; OTTHUMP00000224109; OTTHUMP00000224153;OTTHUMP00000224154; OTTHUMP00000224423; OTTHUMP00000224424;OTTHUMP00000224425; OTTHUMP00000224426; OTTHUMP00000224427;OTTHUMP00000224428; OTTHUMP00000224429; OTTHUMP00000224430; vascularpermeability factor; Vascular endothelial growth factor A; Vascular permeability factor |
Gene ID : | 7422 |
mRNA Refseq : | NM_001025366 |
Protein Refseq : | NP_001020537 |
MIM : | 192240 |
UniProt ID : | P15692 |
Chromosome Location : | 6p12 |
Function : | cell surfacebinding; chemoattractant activity; cytokine activity; extracellular matrixbinding; fibronectin binding; growth factor activity; heparin binding;platelet-derived growth factor receptor binding; protein binding; proteinheterodimerization activity; vascular endothelial growth factor receptor 1binding; vascular endothelial growth factor receptor 2 binding; vascularendothelial growth factor receptor binding |
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◆ Native Protein | ||
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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