Native Human Vitronectin

• Cat.No.: VTN-5410H
• Product Overview: Native humanmonomeric Vitronectin prepared from fresh human plasma using nondenaturingchromatography.

Specification

• Description: The protein encodedby this gene is a member of the pexin family. Vitronectin is an abundantglycoprotein found in serum and the extracellular matrix and promotes celladhesion and spreading, inhibits the membrane-damaging effect of the terminalcytolytic complement pathway, and binds to several serpin serine protease inhibitors.
• Source: Human plasma
• Species: Human
• Form: Liquid in 0.05 Msodium phosphate + 0.1 M NaCl, pH 7.4.
• Molecular Mass: 75.0 kDa
• Storage: Store in workingaliquots at -80°C. Avoid repeated freeze-thaw cycles.
• Concentration: 1.0 mg/ml

Gene Information

• Gene Name: VTN vitronectin [ Homo sapiens ]
• Official Symbol: VTN
• Synonyms: VTN; vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S protein); complement S protein; serum spreading factor; somatomedin B; VN; epibolin; S-protein; complement S-protein; serum-spreading factor; V75; VNT
• Gene ID: 7448
• mRNA Refseq: NM_000638
• Protein Refseq: NP_000629
• MIM: 193190
• UniProt ID: P04004
• Chromosome Location: 17q11.2
• Pathway: ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; FOXA1 transcription factor network, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Inflammatory Response Pathway, organism-specific biosystem
• Function: extracellular matrix binding; heparin binding; integrin binding; polysaccharide binding; scavenger receptor activity