Recombinant Human GCA grancalcin, EF-hand Calcium Binding Protein, His-tagged
Cat.No. : | GCA-2921H |
Product Overview : | Recombinant Human GCA protein was expressed in E.coli with His-tag at the N-terminus. The molecular weight is 24010 Da(217 aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | GCA-2921H |
Description : | Grancalcin is a protein that in humans is encoded by the GCA gene. grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. |
Sequences of amino acids : | 1-217 aa |
Formulation : | 10 mM Tris. pH 8.0. 0.002% NaN3. 3mM NaCl. 2.5mM Imidazole. |
Purity : | 95% |
Gene Name : | GCA grancalcin, EF-hand calcium binding protein [ Homo sapiens ] |
Synonyms : | GCL; grancalcin; OTTHUMP00000204639; OTTHUMP00000204640; grancalcin, penta-EF-hand protein; grancalcin, EF-hand calcium-binding protein |
Gene ID : | 25801 |
mRNA Refseq : | NM_012198 |
Protein Refseq : | NP_036330 |
MIM : | 607030 |
UniProt ID : | P28676 |
Chromosome Location : | 2q37.1 |
Pathway : | Insulin signaling pathway; mTOR signaling pathway |
Function : | calcium ion binding; protein homodimerization activity |
Products Types
◆ Recombinant Protein | ||
GCA-1640R | Recombinant Rhesus Macaque GCA Protein, His (Fc)-Avi-tagged | +Inquiry |
GCA-4787H | Recombinant Human GCA Protein, GST-tagged | +Inquiry |
GCA-1316H | Recombinant Human GCA Protein | +Inquiry |
Gca-3170M | Recombinant Mouse Gca Protein, Myc/DDK-tagged | +Inquiry |
GCA-26242TH | Recombinant Human GCA, His-tagged | +Inquiry |
◆ Native Protein | ||
GCA-2H | Native Human Gastrointestinal Cancer Antigen | +Inquiry |
◆ Lysates | ||
GCA-5994HCL | Recombinant Human GCA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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