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Native Human Thyroid Stimulating Hormone, Beta

Cat.No. : TSHB-704H
Product Overview : Native human TSHB ispurified Human pituitary glands.
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  • Gene Information
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Cat. No. : TSHB-704H
Description : The four humanglycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), folliclestimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimersconsisting of alpha and beta subunits that are associated noncovalently. Thealpha subunits of these hormones are identical, however, their beta chainsare unique and confer biological specificity. Thyroid stimulating hormonefunctions in the control of thyroid structure and metabolism. The proteinencoded by this gene is the beta subunit of thyroid stimulating hormone.Mutations in this gene result in congenital hypothyroidism.
Source : Human pituitaryglands
Form : Lyophilized from0.05 M ammonium bicarbonate.
Concentration : 1.0 mg/mL
Purity : > 98% asdetermined by SDS-PAGE analysis
Reconstitution : Centrifuge vialprior to opening. Add 50 mM Tris, pH 7.5 to the vial to fully solubilize theprotein to a concentration of 1-2 mg/ml.
Storage : Store at -20°C. Avoidrepeated freeze-thaw cycles.
OfficialSymbol : TSHB
Gene Name : TSHB thyroid stimulatinghormone, beta [ Homo sapiens ]
Synonyms : TSHB; thyroidstimulating hormone, beta; TSH-BETA; TSH-B; CHNG4; TSH-beta; Thyrotropinalfa; thyrotropin subunit beta; thyrotropin beta chain; thyrotropin betasubunit; thyroid-stimulating hormone subunit beta
Gene ID : 7252
mRNA Refseq : NM_000549
Protein Refseq : NP_000540
MIM : 188540
UniProt ID : P01222
Chromosome Location : 1p13
Pathway : Amine-derivedhormones; Autoimmune thyroid disease; Class A/1 (Rhodopsin-like receptors); Galpha (s) signalling events; GPCR downstream signaling; GPCR ligand binding;Glycoprotein hormones; Hormone ligand-binding receptors; Metabolism;Metabolism of amino acids and derivatives; Neuroactive ligand-receptorinteraction; Peptide hormone biosynthesis; Signal Transduction; Signaling byGPCR; Thyroxine biosynthesis
Function : hormone activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there specific populations or conditions where TSHB protein assessment is particularly important? 03/09/2023

TSHB protein assessment is crucial in pregnant women, as thyroid function is vital for fetal development, and abnormalities can impact both the mother and the baby.

Can TSHB protein assessment be part of routine health check-ups? 04/19/2021

Yes, measuring TSHB protein levels is often included in routine thyroid function tests during health check-ups.

Can TSHB protein levels be indicative of autoimmune thyroid diseases? 03/08/2019

Yes, elevated TSHB levels may be associated with autoimmune thyroid diseases like Hashimoto's thyroiditis or Graves' disease.

How does the TSHB protein contribute to the management of thyroid cancer? 03/19/2017

TSHB protein levels are monitored to help manage thyroid cancer patients, especially after thyroidectomy, to ensure that thyroid-stimulating hormone levels are within a target range.

Are there advancements in technology or methods for measuring TSHB levels in clinical settings? 06/06/2016

Yes, advancements include highly sensitive immunoassays and molecular techniques that enhance the accuracy and efficiency of TSHB protein measurement.

Customer Reviews (3)

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Reviews
08/25/2021

    Researchers can feel confident in the reliability and efficacy of the TSHB protein and rely on the manufacturer's expertise to navigate any challenges that may arise during their trials.

    07/07/2019

      The manufacturer's commitment to excellence is evident through their provision of excellent technical support, which can prove vital in troubleshooting any experimental challenges or addressing specific research questions related to the protein.

      10/08/2017

        the TSHB protein's quality and suitability for experimental needs, combined with the manufacturer's excellent technical support, create a valuable partnership that enhances research outcomes.

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