Recombinant Human CD1A comprises aa 19-327 is purified by proprietary chromatographic techniques.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants.
Sterile filteredclear solution in 50 mM Tris-Acetate, pH7.5, 1 mM EDTA, 20% Glycerol.
< 0.1ng/ug of protein
ELISA; Western blot; Inhibition Assays
Stable for 1 year. Avoid repeated freeze-thaw cycles.
Store at -80 centigrade. For multiple use, aliquot and freeze at -80 centigrade.