Recombinant Human Phosphomannomutase 1, His-tagged
Cat.No. : | PMM1-803H |
Product Overview : | Recombinant human PMM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 31.9kDa (282aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | PMM1-803H |
Description : | PMM1 (Phosphomannomutase 1) is an enzyme that involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. This enzyme catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. In addition, it may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MAVTAQAARR KERVLCLFDV DGTLTPARQK IDPEVAAFLQ KLRSRVQIGV VGGSDYCKIA EQLGDGDEVI EKFDYVFAEN GTVQYKHGRL LSKQTIQNHL GEELLQDLIN FCLSYMALLR LPKKRGTFIE FRNGMLNISP IGRSCTLEER IEFSELDKKE KIREKFVEAL KTEFAGKGLR FSRGGMISFD VFPEGWDKRY CLDSLDQDSF DTIHFFGNET SPGGNDFEIF ADPRTVGHSV VSPQDTVQRC REIFFPETAH EA |
Formulation : | Liquid, 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 100mM Nacl, 0.1mM PMSF |
Purity : | > 90% by SDS - PAGE |
Concentration : | 0.5mg/ml (determined by Bradford assay) |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | PMM1 phosphomannomutase 1 [Homo sapiens] |
Synonyms : | Phosphomannomutase 1; PMM1; PMMH-22; brain glucose-1,6-bisphosphatase; sec53; EC 5.4.2.8; PMMH-22; PMMH22;OTTHUMP00000028766 |
Gene ID : | 5372 |
mRNA Refseq : | NM_002676 |
Protein Refseq : | NP_002667 |
MIM : | 601786 |
UniProt ID : | Q92871 |
Chromosome Location : | 22q13.2 |
Function : | isomerase activity; metal ion binding; phosphomannomutase activity |
Products Types
◆ Recombinant Protein | ||
PMM1-6874M | Recombinant Mouse PMM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pmm1-4955M | Recombinant Mouse Pmm1 Protein, Myc/DDK-tagged | +Inquiry |
PMM1-1808H | Recombinant Human PMM1, GST-tagged | +Inquiry |
PMM1-13014M | Recombinant Mouse PMM1 Protein | +Inquiry |
PMM1-156H | Recombinant Human PMM1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PMM1-3088HCL | Recombinant Human PMM1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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