Recombinant Human Fibroblast Growth Factor Receptor 3, His-tagged
Cat.No. : | FGFR3-5419H |
Product Overview : | Recombinant humanFGFR3 cytoplasmic domain (amino acids 399-806), His-tagged. No specialmeasures were taken to activate this kinase. |
- Specification
- Gene Information
- Related Products
Cat. No. : | FGFR3-5419H |
Description : | FGFs comprise a family of atleast eighteen structurally realted proteins that are involved in a multitudeof physiological and pathological cellular processes, including cell growth,differentation, angiogenesis, wound healing and tumorgenesis. The biologicalactivities of the FGFs are mediated by a family if type I transmembranetyrosine kinases which undergo dimerization and autophosphorylation afterligand binding. |
Source : | Insect cells |
Species : | Human |
MolecularWeight : | 49.8 kDa |
Form : | Liquid in 50 mMTris, pH 7.5 + 100 mM NaCl + 0.2 mM EDTA + 0.05% Triton X-100 + 5 mM DTT +50% glycerol. |
Purity : | ≥ 90% as determinedby SDS-PAGE analysis |
Specific Activity : | 550 nmoleof phosphate transferred to poly [Glu,Tyr] 4:1 substrate per minute per mg of totalprotein at 30°C. Activity determined at a final protein concentration of 2μg/ml. |
Storage : | Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | FGFR3 |
Gene Name : | FGFR3 fibroblast growth factorreceptor 3 [ Homo sapiens ] |
Synonyms : | FGFR3; fibroblast growth factorreceptor 3; ACH; CEK2; JTK4; CD333; HSFGFR3EX; OTTHUMP00000149958;OTTHUMP00000149959; tyrosine kinase JTK4; hydroxyaryl-protein kinase;achondroplasia, thanatophoric dwarfism; EC 2.7.10.1; FGFR-3; CD333 antigen |
Gene ID : | 2261 |
mRNA Refseq : | NM_000142 |
Protein Refseq : | NP_000133 |
MIM : | 134934 |
UniProt ID : | P22607 |
Chromosome Location : | 4p16.3 |
Pathway : | Bladder cancer; Endocytosis;MAPK signaling pathway; Pathways in cancer; Regulation of actin cytoskeleton;Signaling by FGFR |
Function : | ATP binding; fibroblast growthfactor receptor activity; identical protein binding; nucleotide binding;receptor activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
FGFR3-752H | Recombinant Human FGFR3 Protein, His-tagged, HPLC-verified | +Inquiry |
FGFR3-4136H | Active Recombinant Human FGFR3 Protein, GST-tagged | +Inquiry |
Fgfr3-624M | Active Recombinant Mouse Fgfr3 protein(Met1-Tyr367), His-tagged | +Inquiry |
FGFR3-4137H | Recombinant Human FGFR3 Protein, GST-tagged | +Inquiry |
FGFR3-93H | Recombinant Human FGFR3 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
FGFR3-001CCL | Recombinant Cynomolgus FGFR3 cell lysate | +Inquiry |
FGFR3-2596MCL | Recombinant Mouse FGFR3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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