Catalog # or name ...
Native human APOH wasexpressed in Human plasma.
APOH, also known asbeta2Glycoprotein-1 (B2GP-1) is a plasma glycoprotein that circulates at aconcentration of 200 ug/mL (4mM). B2GP-1 has been identified as a constituentof chylomicrons, very low density lipoproteins and high density lipoproteinsin Human plasma. It has also been demonstrated to bind phospholipids, heparinand platelets where it can modulate the activity of adenylate (19percent).Although the precise functions) are as yet unknown, B2GP-1 has been shown tointerfere with blood coagulation by competitively binding to phospholipidsexposed during cell activation or damage.
Liquid in 0.02MTris-HCI+0.3M NaCI, pH 7.3.
>95% by SDS-PAGEanalysis
When stored at -80oCproduct is stable for 3 years from date of delivery. Avoid repeated freeze-thawcycles.
APOH apolipoprotein H(beta-2-glycoprotein I) [ Homo sapiens ]
APOH; apolipoproteinH (beta-2-glycoprotein I); BG; B2G1; B2GP1; beta-2-glycoprotein 1; B2GPI; apo-H; beta(2)GPI; APC inhibitor; anticardiolipincofactor; activated protein C-binding protein
eukaryotic cell surface binding; glycoprotein binding; heparinbinding; lipid binding; lipoprotein lipase activator activity; phospholipidbinding; protein binding
Derived from PDB structure 1C1Z. Blue regions are positivelycharged and red regions are negatively charged.
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