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   Your Position: Home >> APOH >> Others >> Native Human Apolipoprotein H (beta-2-glycoprotein I)

Native Human Apolipoprotein H (beta-2-glycoprotein I)

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Cat. No.

APOH-5365H

Product Overview

Native human APOH wasexpressed in Human plasma.

Description

APOH, also known asbeta2Glycoprotein-1 (B2GP-1) is a plasma glycoprotein that circulates at aconcentration of 200 ug/mL (4mM). B2GP-1 has been identified as a constituentof chylomicrons, very low density lipoproteins and high density lipoproteinsin Human plasma. It has also been demonstrated to bind phospholipids, heparinand platelets where it can modulate the activity of adenylate (19percent).Although the precise functions) are as yet unknown, B2GP-1 has been shown tointerfere with blood coagulation by competitively binding to phospholipidsexposed during cell activation or damage.

Form

Liquid in 0.02MTris-HCI+0.3M NaCI, pH 7.3.

Source

Human plasma

Molecular Weight

48000

Purity

>95% by SDS-PAGEanalysis

Concentration

1.0 mg/ml

Storage

When stored at -80oCproduct is stable for 3 years from date of delivery. Avoid repeated freeze-thawcycles.

Gene Information

Gene Name

APOH apolipoprotein H(beta-2-glycoprotein I) [ Homo sapiens ]

Official Symbol

APOH

Synonyms

APOH; apolipoproteinH (beta-2-glycoprotein I); BG; B2G1; B2GP1; beta-2-glycoprotein 1; B2GPI; apo-H; beta(2)GPI; APC inhibitor; anticardiolipincofactor; activated protein C-binding protein

GeneID

350

mRNA Refseq

NM_000042

Protein Refseq

NP_000033

MIM

138700

UniProt ID

P02749

Chromosome Location

17q23-qter

Function

eukaryotic cell surface binding; glycoprotein binding; heparinbinding; lipid binding; lipoprotein lipase activator activity; phospholipidbinding; protein binding


APOH(Human),Native Human Apolipoprotein H (beta-2-glycoprotein I)

Derived from PDB structure 1C1Z. Blue regions are positivelycharged and red regions are negatively charged.

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