Native Human Insulin-Like Growth Factor 2 (somatomedin A)
Cat.No. : | IGF2-621H |
Product Overview : | Native human IGF2 is expressed in E. coli, the final productcontains three major isoforms of IGF2 corresponding to MW 16.1, 17.0 and 17.6kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IGF2-621H |
Description : | Human IGF2 is synthesized as a 156 amino acid precursor protein,known as proIGF2. This protein includes an 87 amino acid C-terminal regionknown as the E-domain. A proteolysis step releases the mature 67 amino acidIGF2 polypeptide. The proIGF2 proteins make up 10-20% of circulating IGF2.Pro-IGF2 proteins are secreted by some tumor cell lines and levels areelevated in non-islet cell tumor hypoglycemia. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilizedwhite powder. Dried from 0.1 M acetic acid and stored under dry nitrogen at aslight vacuum (-25 kPa). |
Purity : | 88% |
Biological Activity : | Stimulatesprotein synthesis in rat L6 myoblasts. |
Reconstitution : | Dissolvein dilute acid (10 mM HCl or 0.1 M acetic acid), aliquot and store at -20°C. Avoidrepeated freeze-thaw cycles. For low concentrations (< 1 mg/ml) inclusionof a carrier protein such as BSA is recommended. |
Storage : | Lyophilized protein is stable atleast 2 years at 2-4°C. |
OfficialSymbol : | IGF2 |
Gene Name : | IGF2insulin-like growth factor 2 (somatomedin A) [ Homo sapiens ] |
Synonyms : | IGF2; insulin-likegrowth factor 2 (somatomedin A); IGF-II; PP9974; C11orf43; FLJ22066; FLJ44734;insulin-like growth factor II; somatomedin-A; OTTHUMP00000011012; OTTHUMP00000011013;OTTHUMP00000011015; OTTHUMP00000011016; OTTHUMP00000011017; OTTHUMP00000011018;OTTHUMP00000011157; OTTHUMP00000011158; OTTHUMP000000220667; insulin-likegrowth factor type 2; Insulin-like growth factor II Ala-25 Del; Preptin;PP1446; chromosome 11 open reading frame 43 |
Gene ID : | 3481 |
mRNA Refseq : | NM_000612 |
Protein Refseq : | NP_000603 |
MIM : | 147470 |
UniProt ID : | P01344 |
Chromosome Location : | 11p15.5 |
Pathway : | Apoptosis;Diabetes pathways; Endochondral Ossification; Hedgehog Singling Pathway; Regulationof Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth FactorBinding Proteins (IGFBPs) |
Function : | growthfactor activity; hormone activity; insulin receptor binding; insulin-likegrowth factor receptor binding; protein binding; protein serine/threoninekinase activator activity; receptor activator activity |
Products Types
◆ Recombinant Protein | ||
IGF2-5430H | Recombinant Human Insulin-Like Growth Factor 2 (somatomedin A) | +Inquiry |
IGF2-559H | Recombinant Human IGF2 Protein, Fc-tagged | +Inquiry |
IGF2-99R | Recombinant Rabbit IGF2 Protein | +Inquiry |
IGF2-2661R | Recombinant Rat IGF2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGF2-4461M | Recombinant Mouse IGF2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
IGF2-29116TH | Native Human IGF2 | +Inquiry |
◆ Lysates | ||
IGF2-5266HCL | Recombinant Human IGF2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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