Recombinant Human Insulin-Like Growth Factor 2 (somatomedin A)
| Cat.No. : | IGF2-5431H |
| Product Overview : | Recombinant humanIGF2 was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | IGF2-5431H |
| Description : | The IGF-II geneencodes a single transcript which results in an 156 amino acid protein,including an 89 amino acid E-domain. ProIGF-II contains sites of O-linkedglycosylation. ProIGF-II is converted to mature IGF-II by sequential cleavageafter amino acids 104, 87 and 67. Differential glycosylation and cleavagewithin the E-domain can therefore result in multiple proIGF-II isoforms. |
| Source : | E. coli |
| Species : | Human |
| Purity : | Greater than 95% (byHPLC and N-terminal sequence analysis). |
| Molecular Weight : | 11.949 kDa-confirmedby Mass Spectometry. |
| Endotoxin Level : | Less than 0.1 EU/ug |
| Biological Activity : | Stimulation ofprotein synthesis in rat L6 myoblasts. |
| State and appearance : | Lyophilized whitepowder. |
| N-terminal sequenceanalysis : | 5 residues Greaterthan 95% single sequence. |
| Reconstitution : | Refer to Protocol1000: Handling of GroPep IGF-I, IGF-II and IGF Analogs. |
| Storage : | At least 2 years at2-4°C (lyophilized). |
| OfficialSymbol : | IGF2 |
| Gene Name : | IGF2 insulin-like growth factor2 (somatomedin A) [ Homo sapiens ] |
| Synonyms : | IGF2; insulin-likegrowth factor 2 (somatomedin A); IGF-II; PP9974; C11orf43; FLJ22066; FLJ44734;insulin-like growth factor II;somatomedin-A; OTTHUMP00000011012; OTTHUMP00000011013; OTTHUMP00000011015;OTTHUMP00000011018; OTTHUMP00000011157; OTTHUMP00000011158;OTTHUMP00000220677; insulin-like growth factor type 2 |
| Gene ID : | 3481 |
| mRNA Refseq : | NM_000612 |
| Protein Refseq : | NP_000603 |
| MIM : | 147470 |
| UniProt ID : | P01344 |
| Chromosome Location : | 11p15 |
| Pathway : | Apoptosis;Diabetes pathways; Endochondral Ossification; Hedgehog Signaling Pathway;Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-likeGrowth Factor Binding Proteins (IGFBPs) |
| Function : | growthfactor activity; hormone activity; insulin receptor binding; insulin-likegrowth factor receptor binding; protein binding; protein serine/threoninekinase activator activity; receptor activator activity |
Products Types
| ◆ Recombinant Protein | ||
| IGF2-559H | Recombinant Human IGF2 Protein, Fc-tagged | +Inquiry |
| IGF2-129H | Recombinant Active Human IGF2 Protein, His-tagged(N-ter) | +Inquiry |
| IGF2-058H | Active Recombinant Human IGF2 Protein | +Inquiry |
| Igf2-1224M | Active Recombinant Mouse Igf2 Protein | +Inquiry |
| IGF2-1220H | Recombinant Human IGF2 Protein (30-180 aa), GST-tagged | +Inquiry |
| ◆ Native Protein | ||
| IGF2-29116TH | Native Human IGF2 | +Inquiry |
| IGF2-621H | Native Human Insulin-Like Growth Factor 2 (somatomedin A) | +Inquiry |
| ◆ Lysates | ||
| IGF2-5266HCL | Recombinant Human IGF2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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