Recombinant Rat Plasminogen Activator, Tissue
Cat.No. : | Plat-5462R |
Product Overview : | Recombinant Rat Platand > 85% single chain, > 95% active. |
- Specification
- Gene Information
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Cat. No. : | Plat-5462R |
Description : | Tissue plasminogenactivator (abbreviated tPA or Plat) is a protein involved in the breakdown ofblood clots. It is a serine protease found on endothelial cells, the cellsthat line the blood vessels. As an enzyme, it catalyzes the conversion ofplasminogen to plasmin, the major enzyme responsible for clot breakdown.Because it works on the clotting system, Platis used in clinical medicine to treat only embolic or thrombotic stroke. Useis contraindicated in hemorrhagic stroke and head trauma. |
Source : | Insect cells |
Species : | Rat |
Form : | Liquid in 0.4 MHEPES + 0.1 M NaCl, pH 7.4 |
Molecular Weight : | 70.0 kDa |
Concentration : | 2.0 mg/ml |
Storage : | Store in workingaliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | Plat |
Gene Name : | Plat plasminogen activator,tissue [ Rattus norvegicus ] |
Synonyms : | Plat; plasminogenactivator, tissue; tPA; PATISS; tissue-type plasminogen activator; t-PA;t-plasminogen activator; tissue plasminogen activator; EC 3.4.21.68 |
Gene ID : | 25692 |
mRNA Refseq : | NM_013151 |
Protein Refseq : | NP_037283 |
UniProt ID : | P19637 |
Chromosome Location : | 16q12.5 |
Pathway : | Blood ClottingCascade; Complement and Coagulation Cascades; Dissolution of Fibrin Clot;Endochondral Ossification; Hemostasis; Senescence and Autophagy; SignalTransduction; Signaling by PDGF |
Function : | Molecular function;peptidase activity; serine-type endopeptidase activity |
Products Types
◆ Recombinant Protein | ||
PLAT-8525H | Recombinant Human PLAT protein(Tyr37-Arg310), hFc-tagged | +Inquiry |
Plat-4907M | Recombinant Mouse Plat Protein, Myc/DDK-tagged | +Inquiry |
PLAT-72H | Active Recombinant Human PLAT protein(Ile311-Pro562), hFc-tagged | +Inquiry |
PLAT-1870H | Recombinant Human PLAT Protein, MYC/DDK-tagged | +Inquiry |
PLAT-4154R | Recombinant Rat PLAT Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
PLAT-30920TH | Native Human PLAT | +Inquiry |
PLAT-29690TH | Native Human Human SERPINE1 | +Inquiry |
PLAT-30946TH | Native Human PLAT | +Inquiry |
◆ Lysates | ||
PLAT-2833HCL | Recombinant Human PLAT cell lysate | +Inquiry |
PLAT-1498MCL | Recombinant Mouse PLAT cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0701 | PLAT (Human) Chromogenic Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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