Recombinant Mouse Plasminogen Activator, Tissue
Cat.No. : | Plat-5463M |
Product Overview : | Recombinant Mouse PlatTwo-Chain Active Form is >95% two chain, >95% active. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Plat-5463M |
Description : | Active Two-chainRecombinant Mouse Tissue Plasminogen Activator (Plat/tPA) is produced by activation of the single-chain form with immobilizedPlasmin. Plat is a secreted serine protease whichconverts the proenzyme Plasminogen to the fibrinolytic enzyme Plasmin. Plat is synthesized as a single chain which is cleaved byPlasmin to a two chain disulfide linked protein. This enzyme plays a role incell migration and tissue remodeling. Increased enzymatic activity causeshyperfibrinolysis, which manifests as excessive bleeding; decreased activityleads to hypofibrinolysis which can result in thrombosis or embolism. |
Source : | Insect cells |
Species : | Mouse |
Form : | Frozen Liquid in 0.4M HEPES Buffer + 0.1 M NaCl, pH 7.4 |
Molecular Weight : | 70 kDa |
Concentration : | 2.0 mg/ml |
Purity : | >95% by SDS-PAGEanalysis |
Storage : | Store in workingaliquots at -80°C. Stable for 3 years from delivery. Avoid repeated freeze-thawcycles. |
OfficialSymbol : | Plat |
Gene Name : | Plat plasminogen activator,tissue [ Mus musculus ] |
Synonyms : | Plat; plasminogenactivator, tissue; tPA; AU020998; AW212668; D8Ertd2e; MGC18508; tissue-typeplasminogen activator; t-plasminogen activator; EC 3.4.21.68 |
Gene ID : | 18791 |
mRNA Refseq : | NM_008872 |
Protein Refseq : | NP_032898 |
UniProt ID : | P11214 |
Chromosome Location : | 8 A2; 8 9.0 cM |
Pathway : | Blood ClottingCascade; Complement and Coagulation Cascades; Dissolution of Fibrin Clot;Endochondral Ossification; Hemostasis; Senescence and Autophagy; SignalTransduction; Signaling by PDGF |
Function : | catalytic activity;hydrolase activity; peptidase activity; serine-type endopeptidase activity;serine-type peptidase activity |
Products Types
◆ Recombinant Protein | ||
PLAT-1870H | Recombinant Human PLAT Protein, MYC/DDK-tagged | +Inquiry |
PLAT-5461H | Recombinant Human Plasminogen Activator, Tissue | +Inquiry |
Plat-4907M | Recombinant Mouse Plat Protein, Myc/DDK-tagged | +Inquiry |
PLAT-4154R | Recombinant Rat PLAT Protein, His (Fc)-Avi-tagged | +Inquiry |
Plat-5462R | Recombinant Rat Plasminogen Activator, Tissue | +Inquiry |
◆ Native Protein | ||
PLAT-30920TH | Native Human PLAT | +Inquiry |
PLAT-29690TH | Native Human Human SERPINE1 | +Inquiry |
PLAT-30946TH | Native Human PLAT | +Inquiry |
◆ Lysates | ||
PLAT-1498MCL | Recombinant Mouse PLAT cell lysate | +Inquiry |
PLAT-2833HCL | Recombinant Human PLAT cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0701 | PLAT (Human) Chromogenic Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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