Native Rat Natriuretic Peptide B
Cat.No. : | Nppb-5459R |
Product Overview : | Nppb is a 32 aapeptide secreted by the ventricles of the heart in response to excessive stretching of myocytes in the ventricles. A high concentration of thisprotein in the bloodstream is indicative of heart failure. |
- Specification
- Gene Information
- Related Products
Description : | Native Rat Nppb, also known as BrainNatriuretic Peptide-32 (BNP32) is a member of the natriuretic peptide familyand is a secreted protein which functions as a cardiac hormone. The proteinundergoes two cleavage events, one within the cell and a second aftersecretion into the blood. The protein"s biological actions includenatriuresis, diuresis, vasorelaxation, inhibition of renin and aldosteronesecretion, and a key role in cardiovascular homeostasis. |
Source : | Rat |
Species : | Rat |
Form : | TrifluoroacetateSalt. |
AA Sequence : | Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys-Phe-Gly-Gln-Lys-lle-Asp-Arg-lle-Gly -Ala-Val-Ser-Arg-Leu-Gly-Cys-Asp-Gly-Leu-Arg-Leu-Phe |
Purity : | ≥99% |
Storage : | Store at -20°C. |
Gene Name : | Nppb natriuretic peptide B [ Rattus norvegicus ] |
Official Symbol : | Nppb |
Synonyms : | NPPB; natriuretic peptide B; natriuretic peptides B; iso-ANP; Brain natriuretic factor; brain natriuretic peptide; gamma-brain natriuretic peptide; natriuretic peptide precursor B; natriuretic peptide precursor type B; BNP; Bnf; |
Gene ID : | 25105 |
mRNA Refseq : | NM_031545 |
Protein Refseq : | NP_113733 |
Chromosome Location : | 5q36 |
Function : | hormone activity; peptide hormone receptor binding; receptor binding; |
Products Types
◆ Recombinant Protein | ||
NPPB-1298H | Recombinant Human NPPB Protein, GST-tagged | +Inquiry |
Nppb-390R | Recombinant Rat Nppb Protein, His&SUMO-tagged | +Inquiry |
Nppb-1852M | Recombinant Mouse Nppb Protein, His&GST-tagged | +Inquiry |
NPPB-388H | Recombinant Human NPPB Protein, His&SUMO-tagged | +Inquiry |
NPPB-2826H | Recombinant Human NPPB Protein, His-tagged, OVA Conjugated | +Inquiry |
◆ Native Protein | ||
NPPB-8052R | Native Rat Brain Natriuretic Peptide-32 | +Inquiry |
◆ Lysates | ||
NPPB-3734HCL | Recombinant Human NPPB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionElevated NPPB levels are associated with fluid overload, providing valuable information for clinicians in managing patients with conditions like edema.
Yes, monitoring NPPB levels over time can help assess the effectiveness of treatments and interventions in managing cardiovascular conditions.
Normal ranges of NPPB may vary with age and gender. Understanding these variations is essential for accurate clinical interpretation.
While NPPB is a valuable marker, clinicians should consider factors like renal function and comorbidities that may affect its interpretation.
NPPB regulates blood pressure by promoting vasodilation and natriuresis. Understanding its levels can guide the management of hypertension.
Customer Reviews (3)
Write a reviewThey actively engage with researchers, comprehending their specific experimental needs, and offering tailored services accordingly.
This collaborative partnership facilitates a seamless and efficient research process, as the manufacturer aligns their support and services with my unique requirements.
The manufacturer's excellent technical support, commitment to innovation, and customer-centric approach further reinforce its suitability for my research.
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