Recombinant Macaca mulatta Interleukin 8
Cat.No. : | IL8-5434M |
Product Overview : | Recombinant RhesusMonkey IL8 is expressed in E. coli. |
- Specification
- Gene Information
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Cat. No. : | IL8-5434M |
Description : | IL8, also named CXCL8, monocyte-derivedneutrophil chemotactic factor (MDNCF), neutrophil-activating protein 1(NAP1), neutrophil-activating factor (NAF) and granulocyte chemotacticpeptide (GCP), belongs to the Glu-Leu-Arg motif containing (ELR+)CXC chemokine family and has been designated CXCL8. IL8 is a potentneutrophil chemoattractant that recruits neutrophils to sites ofinflammation. IL8 also activates neutrophil functions and promotesangiogenesis. |
Source : | E. coli |
Species : | Macaca mulatta |
Form : | Lyophilized from a0.2µm filtered concentrated solution in PBS, pH 7.4. |
MolecularWeight : | Approximately 9.1kDa, a single non-glycosylated polypeptide chain containing 79 amino acids. |
Purity : | > 97% by SDS-PAGEand HPLC analyses |
Endotoxin Level : | Less than 1EU/µg ofrRh IL8 as determined by LAL method. |
Biological Activity : | Determined by itsability to chemoattract human peripheral blood neutrophils using aconcentration range of 25-150 ng/ml. |
Sequences : | AVLPRSAKELRCECIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE PWVQRVVEKF VKRAENQNP |
Reconstitution : | We recommend thatthis vial be briefly centrifuged prior to opening to bring the contents tothe bottom. Reconstitute in sterile distilled water or aqueous buffercontaining 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutionsshould be apportioned into working aliquots and stored at ≤-20°C. Furtherdilutions should be made in appropriate buffered solutions. |
Storage : | This lyophilizedpreparation is stable at 2-8°C, but should be kept at -20°C for long termstorage, preferably desiccated. Upon reconstitution, the preparation isstable for up to one week at 2-8°C. For maximal stability, apportion thereconstituted preparation into working aliquots and store at -20°C to -80°C.Avoid repeated freeze/thaw cycles. |
OfficialSymbol : | IL8 |
Gene Name : | IL8 interleukin 8 [ Macacamulatta ] |
Synonyms : | IL8; interleukin 8;interleukin-8; IL-8; C-X-C motif chemokine 8 |
Gene ID : | 613028 |
mRNA Refseq : | NM_001032965 |
Protein Refseq : | NP_001028137 |
UniProt ID : | P67813 |
Chromosome Location : | 5 |
Pathway : | Amoebiasis; Bladder cancer; Chemokinesignaling pathway; Cytokine-cytokine receptor interaction; Hepatitis C; HepatitisA; Legionellosis; Malaria; NOD-like receptor signaling pathway; Pathways incancer; Pertussis; RIG-I-like receptor signaling pathway; Rheumatoidarthritis; Salmonella infection; Toll-like receptor signaling pathway |
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◆ Lysates | ||
IL8-3004HCL | Recombinant Human IL8 cell lysate | +Inquiry |
IL8-3002HCL | Recombinant Human IL8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionActs as a chemical messenger in the immune system that regulates inflammation and attracts immune cells such as white blood cells.
Regulating tumor microenvironment, promoting tumor growth and metastasis, and can be used in tumor therapy research.
IL8 plays a role in regulating and promoting the migration and activation of inflammatory cells in the inflammatory response.
Can be used to treat inflammatory diseases (such as rheumatoid arthritis, psoriasis), tumors (such as lung cancer, breast cancer) and other diseases.
Yes, IL8 is closely related to immunotherapy, which can enhance the role of the immune system and assist in the treatment of certain diseases.
IL8 is generally prepared by gene recombination technology, and the IL8 gene is introduced into the appropriate expression system, and then expressed and purified.
Customer Reviews (3)
Write a reviewIL8 has good fluorescence and absorption properties.
NIPBL has good stability in different environments and is not easy to degrade.
Through animal models or in vitro experiments to evaluate the mechanism of the recombinant protein in related diseases, we found that the effect is very good.
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