Recombinant Human Kinase Insert Domain Receptor (a type III receptor tyrosine kinase), His-tagged

• Cat.No.: KDR-5443H
• Product Overview: Recombinant humanKDR catalytic domain (amino acids 789-1356), His-tagged. Activated in vitrovia auto-phosphorylation.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 789-1356 a.a.
• Description: KDRalso known as vascular endothelial growth factor receptor 2 (VEGFR-2) is aVEGF receptor. KDR is the human gene encoding it. KDR has also beendesignated as CD309 (cluster of differentiation 309). KDR is also known asFlk1 (Fetal Liver Kinase 1).
• Form: Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.25 mM EDTA + 0.01% Triton X-100 + 2 mM DTT +50% glycerol.
• Molecular Weight: 68.4 kDa
• Storage: Stablefor 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: KDR kinase insert domain receptor (a typeIII receptor tyrosine kinase) [ Homo sapiens ]
• Official Symbol: KDR
• Synonyms: KDR; kinase insertdomain receptor (a type III receptor tyrosine kinase); FLK1;CD309; VEGFR; VEGFR2; vascular endothelial growth factor receptor 2; solubleVEGFR2; OTTHUMP00000158928; fetal liver kinase 1; fetal liver kinase-1;protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factorreceptor
• Gene ID: 3791
• mRNA Refseq: NM_002253
• Protein Refseq: NP_002244
• MIM: 191306
• UniProt ID: P35968
• Chromosome Location: 4q11-q12
• Pathway: Cytokine-cytokine receptorinteraction; Endocytosis; Focal adhesion; VEGF signaling pathway; Signalingby VEGF
• Function: ATP binding; growth factorbinding; nucleotide binding; receptor activity; transferase activity;vascular endothelial growth factor receptor activity