Recombinant Human CTD (Carboxy-Terminal Domain, RNA Polymerase II, Polypeptide A) Small, Phosphatase 1, His-tagged
Cat.No. : | CTDSP1-975H |
Product Overview : | Recombinant human CTDSP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CTDSP1-975H |
Description : | Carboxy-terminal domain, RNA polymerase II, polypeptide A phosphatase 1, also known as CTDSP1, is a class 2C phosphatase with activity dependent on the conserved DxD motif. CTDSP1 preferentially catalyzes the dephosphorylation of "Ser-5" within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Also it negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. |
Formulation : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl |
Purity : | > 90% by SDS - PAGE |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Sequences of animo acids : | MGSSHHHHHH SSGLVPRGSHMDSSAVITQI SKEEARGPLR GKGDQKSAAS QKPRSRGILH SLFCCVCRDD GEALPAHSGA PLLVEENGAIPKTPVQYLLP EAKAQDSDKI CVVIDLDETL VHSSFKPVNN ADFIIPVEID GVVHQVYVLK RPHVDEFLQR MGELFECVLF TASLAKYADP VADLLDKWGA FRARLFRESC VFHRGNYVKD LSRLGRDLRR VLILDNSPAS YVFHPDNAVP VASWFDNMSD TELHDLLPFF EQLSRVDDVYSVLRQPRPGS |
Storgage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles. |
Gene Name : | CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 [ Homo sapiens ] |
Synonyms : | CTDSP1;CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small,phosphatase 1;small CTD phosphatase 1;NLI-interacting factor 3;small C-terminal domain phosphatase 1;nuclear LIM interactor-interacting factor 3;carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1;SCP1; NLIIF; CTDSP1;nuclear LIMinteractor-interacting factor;small CTD phosphatase 1;EC 3.1.3.16;NIF3;NLI-IF;CTD (carboxy-terminal domain, RNA polymerase II,NLI-interacting factor 3 |
Gene ID : | 58190 |
mRNA Refseq : | NM_021198 |
Protein Refseq : | NP_067021 |
MIM : | 605323 |
UniProt ID : | Q9GZU7 |
Chromosome Location : | 2q35 |
Function : | CTD phosphatase activity;hydrolase activity;metal ion binding;phosphoprotein phosphatase activity;protein binding |
Products Types
◆ Recombinant Protein | ||
CTDSP1-2047M | Recombinant Mouse CTDSP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CTDSP1-2060H | Recombinant Human CTDSP1 Protein, GST-tagged | +Inquiry |
CTDSP1-899R | Recombinant Rhesus Macaque CTDSP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ctdsp1-2354M | Recombinant Mouse Ctdsp1 Protein, Myc/DDK-tagged | +Inquiry |
CTDSP1-28022TH | Recombinant Human CTDSP1, His-tagged | +Inquiry |
◆ Lysates | ||
CTDSP1-7210HCL | Recombinant Human CTDSP1 293 Cell Lysate | +Inquiry |
CTDSP1-7211HCL | Recombinant Human CTDSP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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