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Recombinant Human Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-cells Inhibitor, Beta, His-tagged

Cat.No. : NFKBIB-5544H
Product Overview : Recombinant humanNFKBIB protein, fused to His-tag at N-terminus, was expressed in E. coliand purified by using conventional chromatography.
  • Specification
  • Gene Information
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Cat. No. : NFKBIB-5544H
Description : NFKBIB, also knownas NF-kappa-B inhibitor beta, belongs to the NF-kappa-B inhibitor family,which inhibit NF-kappa-B by complexing with, and trapping it in thecytoplasm. Phosphorylation of serine residues on these proteins by kinasesmarks them for destruction via the ubiquitination pathway, thereby allowingactivation of the NF-kappa-B, which translocates to the nucleus to functionas a transcription factor.
Form : Liquid. 20mMTris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT.
Molecular Weight : 40.3 kDa (380aa),confirmed by MALDI-TOF.
Purity : > 90%by SDS-PAGE
Concentration : 1 mg/ml(determined by Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSHMAGVAC LGKAADADEW CDSGLGSLGP DAAAPGGPGL GAELGPGLSWAPLVFGYVTE DGDTALHLAV IHQHEPFLDF LLGFSAGTEY MDLQNDLGQT ALHLAAILGE TSTVEKLYAAGAGLCVAERR GHTALHLACR VGAHACARAL LQPRPRRPRE APDTYLAQGP DRTPDTNHTP VALYPDSDLEKEEEESEEDW KLQLEAENYE GHTPLHVAVI HKDVEMVRLL RDAGADLDKP EPTCGRSPLH LAVEAQAADVLELLLRAGAN PAARMYGGRT PLGSAMLRPN PILARLLRAH GAPEPEGEDE KSGPCSSSSD SDSGDEGDEYDDIVVHSSRS QTRLPPTPAS KPLPDDPRPV
Storage : Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
OfficialSymbol : NFKBIB
nullValue_other :
PathwaysActivated TLR4signalling; Adipocytokine signaling pathway; Apoptosis; B cell receptorsignaling pathway; BCR signaling pathway; Chemokine signaling pathway;Cytosolic DNA-sensing pathway; Herpes simplex infection; Immune System;Influenza A; Innate Immune System; Leishmaniasis; Measles; MyD88 cascadeinitiated on plasma membrane; NFkB and MAP kinases activation mediated byTLR4 signaling repertoire
Gene Name : NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor,beta [ Homo sapiens ]
Synonyms : NFKBIB; nuclearfactor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; IKBB;TRIP9; NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9
Gene ID : 4793
mRNA Refseq : NM_002503
Protein Refseq : NP_002494
MIM : 604495
UniProt ID : Q15653
Chromosome Location : 19q13.1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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