Recombinant Human CDC6, GST-tagged
Cat.No. : | CDC6-96H |
Product Overview : | Recombinant human CDC6 encoding human CDC6 partial ORF (434a.a. - 533 a.a.) produced in in vitro wheat germ expression system, was fuseda GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CDC6-96H |
Description : | The protein encoded by this gene is highlysimilar to Saccharomyces cerevisiae Cdc6, a protein essential for theinitiation of DNA replication. This protein functions as a regulator at theearly steps of DNA replication. It localizes in cell nucleus during cell cyleG1, but translocates to the cytoplasm at the start of S phase. Thesubcellular translocation of this protein during cell cyle is regulatedthrough its phosphorylation by Cdks. Transcription of this protein wasreported to be regulated in response to mitogenic signals throughtranscriptional control mechanism involving E2F proteins. |
Source : | wheat germ |
Sequence : | ISQVISEVDGNRMTLSQEGAQDSFP LQQKILVCSLMLLIRQLKIKEVTLG KLYEAYSKVCRKQQVAAVDQSECLS LSGLLEARGILGLKRNKETRLTKVF |
Purification : | GlutathioneSepharose 4 Fast Flow |
Molecular Weight : | 36.74 kDa |
Applications : | ELISA;WB |
StorageBuffer : | 50 mM Tris-HCI, 10mM reduced Glutathione, pH8.0 in the elution buffer. |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | CDC6cell division cycle 6 homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | CDC6 |
Synonyms : | CDC6; cell division cycle 6 homolog (S. cerevisiae);CDC18L; HsCDC6; HsCDC18; CDC6 (cell division cycle 6, S. cerevisiae) homolog;CDC6 cell division cycle 6 homolog (S. cerevisiae); Cell division controlprotein 6 homolog; p62(cdc6); CDC18 (cell division cycle 18, S.pombe,homolog)-like; homolog; CDC6 cell division cycle 6 homo; CDC6-relatedprotein; cell division cycle 6 homolog (S. cerevisiae); cell division cycle 6protein |
Gene ID : | 990 |
mRNA Refseq : | NM_001254 |
Protein Refseq : | NP_001245 |
MIM : | 602627 |
UniProt ID : | Q99741 |
Chromosome Location : | 17q21.3 |
Pathway : | Activation of ATRin response to replication stress; Cell Cycle, Mitotic; DNA Replication |
Products Types
◆ Recombinant Protein | ||
CDC6-1493M | Recombinant Mouse CDC6 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC6-6781Z | Recombinant Zebrafish CDC6 | +Inquiry |
CDC6-93H | Recombinant Human cell division cycle 6 homolog (S. cerevisiae) | +Inquiry |
CDC6-3152M | Recombinant Mouse CDC6 Protein | +Inquiry |
CDC6-022H | Recombinant Human CDC6 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CDC6-7647HCL | Recombinant Human CDC6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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