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Active Recombinant Human Intercellular Adhesion Molecule 5, Telencephalin, Fc-tagged

Cat.No. : ICAM5-5642H
Product Overview : RecombinantHuman ICAM5 protein was expressed in Murine myeloma cell line with the Fcpart of Human IgG1 Pro100-Lys330 (C-terminus) and Human ICAM5 Ala28-Glu570(N-terminus).
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  • Gene Information
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Cat. No. : ICAM5-5642H
Description : ICAM5 isa cell surface glycoprotein belonging to the immunoglobulin superfamily.Human ICAM5 consists of an 832 amino acid (aa) extracellular domaincontaining 9 immunoglobulin (Ig) domains and 15 N-glycosylation sites, a 28aa transmembrane domain, and a 64 aa cytoplasmic domain. ICAM5 shares 38-55%aa identity with other ICAMs, being most closely related to ICAM-1 (50% identity)and ICAM-3 (55% identity). Human and mouse ICAM5 share 85% aa identity.
Source : Mammalian cells
Form : Lyophilizedfrom a 0.2 um filtered solution in PBS.
N-terminalSequence : Ala28
MolecularWeight : 85.1 kDa (monomer)
Activity : Measuredby the ability of the immobilized protein to support the adhesion ofPMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemiacells. When 5x104 cells/well are added to rhICAM5/Fc Chimeracoated plates (25 μg/mL, 100 μL/well), approximately 25-40% will adhere after1 hour incubation at 37°C.
Endotoxin Level : <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE : 125-130kDa, reducing conditions.
Purity : >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : 400 μg/mLin sterile PBS
Storage : Use a manualdefrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : ICAM5intercellular adhesion molecule 5, telencephalin [ Homo sapiens ]
Official Symbol : ICAM5
Synonyms : ICAM5; intercellularadhesion molecule 5, telencephalin; TLN; TLCN; intercellular adhesionmolecule 5; ICAM-5; telencephalin
Gene ID : 7087
mRNA Refseq : NM_003259
Protein Refseq : NP_003250
MIM : 601852
UniProt ID : Q60625
Chromosome Location : 19p13.2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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