Active Recombinant Human Bone Morphogenetic Protein 1, His-tagged
Cat.No. : | BMP1-571H |
Product Overview : | Recombinant Human BMP1protein was expressed in Murine myeloma cell line with a C-terminal 6-His tag.Ala121-Gln730. |
- Specification
- Gene Information
- Related Products
Cat. No. : | BMP1-571H |
Description : | Bone morphogeneticprotein 1 (BMP1), also known as procollagen Cproteinase (PCP), is a zinc proteaseof the astacin family. BMP1/PCP plays a key role in formation ofextracellular matrix (ECM) by converting precursor proteins into their matureand functional forms. The precursor proteins identified as substrates forBMP1/PCP include collagens, biglycan, laminin 5, dentin matrix protein1, andlysyl oxidase. There are six alternatively spliced forms known to be derivedfrom the BMP1 gene, and isoform 1 consisting of residues 1 to 730 wasexpressed. |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 μm filtered solution in HEPES, NaCl, CaCl2, ZnCl2and Brij-35. |
N-terminalSequence : | Ala121 |
Molecular Weight : | 70.5 kDa |
Activity : | Measured by itsability to cleave a fluorogenic peptide substrate, Mca-YVADAPK (Dnp)-OH. Thespecific activity is > 4 pmol/min/μg, as measured under the describedconditions. |
Endotoxin Level : | < 1.0EU per 1 μg of the protein by the LAL method. |
SDS-PAGE : | 84 kDa, reducingconditions. |
Purity : | > 95%, by SDSPAGEunder reducing conditions and visualized by silver stain. |
Reconstitution : | 100 μg/mL in sterile25 mM HEPES and 0.01% Brij-35, pH 7.5. |
Storage : | Use a manual defrostfreezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt,-20 to -70°C as supplied. 3 months, -20 to -70°C under sterile conditionsafter reconstitution. |
Gene Name : | BMP1 bone morphogenetic protein 1[ Homo sapiens ] |
Official Symbol : | BMP1 |
Synonyms : | BMP1; bonemorphogenetic protein 1; procollagen C-proteinase; mammalian tolloid protein;procollagen C-endopeptidase; BMP-1; PCP; PCOLC; mTId; EC 3.4.24.19 |
Gene ID : | 649 |
mRNA Refseq : | NM_001199 |
Protein Refseq : | NP_001190 |
MIM : | 112264 |
UniProt ID : | P13497 |
Chromosome Location : | 8p21 |
Pathway : | Adipogenesis;HDL-mediated lipid transport; Lipid digestion; Lipoprotein metabolism;Metabolism; Metabolism of lipids and lipoproteins |
Function : | calcium ion binding;cytokine activity; growth factor activity; metal ion binding;metalloendopeptidase activity; metallopeptidase activity; peptidase activity;zinc ion binding |
Products Types
◆ Recombinant Protein | ||
BMP1-2548H | Recombinant Human BMP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMP1-374R | Recombinant Rhesus Macaque BMP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMP1-1050M | Recombinant Mouse BMP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMP1-546R | Recombinant Rhesus monkey BMP1 Protein, His-tagged | +Inquiry |
BMP1-2428M | Recombinant Mouse BMP1 Protein | +Inquiry |
◆ Lysates | ||
BMP1-8436HCL | Recombinant Human BMP1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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