Active Recombinant Mouse Furin (paired basic amino acid cleaving enzyme)
Cat.No. : | Furin-566M |
Product Overview : | Recombinantmouse Furin protein was expressed in Chinese Hamster Ovary cell line, CHO-derived,with an N-terminus human CD33 signal peptide and a C-terminal 10-His tag. Gln25-Glu714. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Furin-566M |
Description : | Furin is a member ofthe proprotein convertase (PC) family, which belongs to the subtilisinsuperfamily of serine proteases. As a cellular protease, Furin processes avariety of proproteins in secretory pathway compartments by cleaving after Arg-Xaa-Lys/Arg-Arg-like motifs, which usually reside at the end of the pro regions ofthese proproteins. |
Source : | Chinese HamsterOvary cell line, CHO-derived |
Form : | Supplied as a 0.2 μmfiltered solution in Tris, CaCl2, NaCl, Brij-35 and Glycerol. |
N-terminal Sequence : | Asp108, Cys198,Ser239, Glu684 |
Molecular Weight : | 77 kDa |
Activity : | Measured by itsability to cleave the fluorogenic peptide substrate pERTKR-AMC. The specificactivity is > 150 pmoles/min/μg, as measured under the described conditions. |
Endotoxin Level : | <1.0 EU per 1 μgof the protein by the LAL method. |
SDS-PAGE : | 60-80 kDa, reducingconditions |
Purity : | >95%, by SDS-PAGEunder reducing conditions and visualized by Colloidal Coomassie® Blue stainat 5 μg per lane. |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3months, -20 to -70 °C under sterile conditions after reconstitution. |
Gene Name : | Furin furin (paired basic aminoacid cleaving enzyme) [ Mus musculus ] |
Official Symbol : | Furin |
Synonyms : | Furin; furin (pairedbasic amino acid cleaving enzyme); OTTMUSP00000036135; OTTMUSP00000036136;OTTMUSP00000036137; OTTMUSP00000036138; Fur; PACE; SPC1; Pcsk3; 9130404I01Rik;prohormone convertase 3; diabasic-processing enzyme; substilisin pro-proteinprocessing enzyme; proprotein convertase substilisin/kexin type 3; pariedbasic amino acid residue cleaving enzyme; paried basic amino acidresidue-cleaving enzyme; EC 3.4.21.75 |
Gene ID : | 18550 |
mRNA Refseq : | NM_001081454 |
Protein Refseq : | NP_001074923 |
UniProt ID : | P23188 |
Chromosome Location : | 7 |
Pathway : | Delta-Notch Signaling Pathway;Gamma-carboxylation, transport, and amino-terminal cleavage of proteins;Influenza A; Maturation of Notch precursor via proteolytic cleavage;Metabolism of proteins; NGF processing; PTM: gamma carboxylation, hypusineformation and arylsulfatase activation; Post-translational proteinmodification; Removal of aminoterminal propeptides from gamma-carboxylatedproteins; Signal Transduction, Signaling by Notch; Signaling by PDGF; Signalingby TGF beta; Signalling by NGF |
Function : | endopeptidase activity; hydrolase activity;metal ion binding; nerve growth factor binding; peptidase activity; peptidebinding; protease binding; protein binding; serine-type endopeptidaseactivity; serine-type endopeptidase inhibitor activity; serine-type peptidaseactivity |
Products Types
◆ Recombinant Protein | ||
FURIN-946H | Recombinant Human FURIN Protein, His (Fc)-Avi-tagged | +Inquiry |
FURIN-4553H | Active Recombinant Human FURIN Protein | +Inquiry |
FURIN-30H | Recombinant Human FURIN Protein (AA 27-715), C-GFP/His-Tagged | +Inquiry |
FURIN-605H | Active Recombinant Human FURIN Protein | +Inquiry |
FURIN-2066R | Recombinant Rat FURIN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FURIN-6119HCL | Recombinant Human FURIN 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionCustomer Reviews (3)
Write a reviewThe proteins purchased from your company are of very high quality and are suitable for WB experiments.
High quality product at a good price, a satisfactory shopping experience.
The staff were enthusiastic and proactive in communicating with me and solving many technical problems in a timely manner.
Ask a Question for All Furin Products
Required fields are marked with *
My Review for All Furin Products
Required fields are marked with *
Inquiry Basket