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Active Recombinant Mouse Fc receptor-like 5, His-tagged

Cat.No. : Fcrl5-503M
Product Overview : RecombinantMouse Fcrl5 protein was expressed in Murine myeloma cellline. Met1-Ala496,with a C-terminal 6-His tag.
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Cat. No. : Fcrl5-503M
Description : Fcrl5 is a 90-95kDa member of the FCRL family of proteins whose amino acid (aa) sequence isreminiscent of that for classical Fc receptors. FCLR molecules are type 1transmembrane proteins that contain from 3 to 9 immunoglobulin-like domains.They are differentially expressed within the B cell lineage, and can eitherpromote or inhibit B cell proliferation and activation. Mature mouse Fcrl5 consistsof a 470 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a79 aa cytoplasmic region. The ECD contains five Iglike domains, while the cytoplasmicregion possesses one ITAM-like motif and one immunotyrosine inhibitory motif(ITIM).
Source : Mammalian cells
Form : Lyophilized from a0.2 um filtered solution in PBS.
N-terminalSequence : Gln27 predicted
MolecularWeight : 53.5 kDa
Activity : Measuredby its ability to bind mouse IgG with an estimated KD < 400 nM.
Endotoxin Level : <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE : 65-80kDa, reducing conditions.
Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100μg/mLin PBS.
Storage : Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.
Gene Name : Fcrl5 Fc receptor-like 5 [ Musmusculus ]
Official Symbol : Fcrl5
Synonyms : Fcrl5; Fcreceptor-like 5; Fcrh3; mBXMH2; Fcreceptor-like protein 5; moFcRH3; fcR-like protein 5; BXMAS1-like protein 2;fc receptor homolog 3; Fc receptor-like protein 3
Gene ID : 329693
mRNA Refseq : NM_001113238
Protein Refseq : NP_001106709
UniProt ID : Q68SN8
Chromosome Location : 3
Pathway : T Cell ReceptorSignaling Pathway
Function : molecular_function;receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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