Active Recombinant Human Fc Receptor-Like 5, His-tagged
Cat.No. : | FCRL5-506H |
Product Overview : | RecombinantHuman FCRL5 protein was expressed in Murine myeloma cellline. Gln16-Arg844,with a C-terminal 6-His tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | FCRL5-506H |
Description : | FCRL5 isa 120 kDa protein with sequence homology to classical Fc receptors. They are differentiallyexpressed within the B cell lineage and can either promote or inhibit B cellproliferation and activation. According to R&D Systems testing, FCRL5binds to purified human IgG with high affinity. Mature human FCRL5 consistsof a 836 amino acid (aa) extracellular domain (ECD) with nine Ig-like domains,a 21 aa transmembrane segment, and a 105 aa cytoplasmic domain with one immunotyrosineactivation motif (ITAM) and two immunotyrosine inhibitory motifs (ITIMs). |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 um filtered solution in PBS. |
N-terminalSequence : | Gln16 predicted |
MolecularWeight : | 91.5 kDa |
Activity : | Measuredby its ability to bind human IgG with an estimated KD < 30 nM. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 110-120kDa, reducing conditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstitute at 100μg/mLin PBS. |
Storage : | Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution. |
Gene Name : | FCRL5 Fc receptor-like 5 [ Homosapiens ] |
Official Symbol : | FCRL5 |
Synonyms : | FCRL5;Fc receptor-like 5; Fc receptor-like protein 5; BXMAS1; CD307e; FCRH5; IRTA2;BXMAS1; CD307 antigen; Fc receptor homolog 5; Fc receptor like 5; FcR-likeprotein 5; FCRL5_HUMAN; Immune receptor translocation-associated protein 2;Immunoglobulin receptor translocation associated gene 2 protein;Immunoglobulin superfamily receptor translocation associated gene 2 protein;UNQ503/PRO820; immunoglobulin superfamily receptor translocation associated 2(IRTA2); CD307; PRO820; RP11-217A12.1 |
Gene ID : | 83416 |
mRNA Refseq : | NM_001195388 |
Protein Refseq : | NP_001182317 |
MIM : | 605877 |
UniProt ID : | Q96RD9 |
Chromosome Location : | 1q21 |
Function : | receptor activity |
Products Types
◆ Recombinant Protein | ||
FCRL5-4010H | Recombinant Human FCRL5 Protein | +Inquiry |
Fcrl5-3196M | Recombinant Mouse Fcrl5 Protein, His (Fc)-Avi-tagged | +Inquiry |
FCRL5-4011H | Recombinant Human FCRL5 Protein, GST-tagged | +Inquiry |
FCRL5-2940H | Recombinant Human FCRL5 Protein, His (Fc)-Avi-tagged | +Inquiry |
FCRL5-1708R | Recombinant Rhesus Monkey FCRL5 Protein, hIgG4-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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