Active Recombinant Human Fibroblast Growth Factor Binding Protein 1, His-tagged
Cat.No. : | FGFBP1-548H |
Product Overview : | Recombinant Human FGFBP1protein was expressed in Murine myeloma cell line with a C-terminal 10-Histag. Lys24-Cys234 & Asn29-Cys234. |
- Specification
- Gene Information
- Related Products
Cat. No. : | FGFBP1-548H |
Description : | Fibroblast growthfactor binding protein (FGFBP1), also known as HBP17, is a secretedglycoprotein that increases the bioavailability of FGFs. Mature FGFBP1 is a34 kDa, 211 amino acids (aa) O-glycosylated protein with five conserved intrachaindisulfide bonds. FGFBP1 contains a heparinbinding domain (aa 110-143) and adistinct FGF binding region (aa 193-243). Mature human FGFBP1 shares 59% and54% aa sequence identity with mouse and rat FGFBP1, respectively. FGFBP1 isexpressed throughout development and in adult squamous epithelium. |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 μm filtered solution in PBS. |
N-terminalSequence : | Lys24 & Asn29 |
Molecular Weight : | 25.2 kDa& 24.6 kDa |
Activity : | Measuredby its binding ability in a functional ELISA. 1 μg/mL of rhFGFBP1 was mixedwith serially diluted rhFGF basic. Following incubation, the FGFBP-FGF basiccomplex was captured on a Gt x hFGFBP-coated plate. Bound FGF basic wasmeasured using biotinylated Gt x hFGF basic. The concentration of rhFGF basicthat produces 50% of the optimal binding was found to be approximately 5-20ng/mL. |
Endotoxin Level : | <1.0 EUper 1 μg of the protein by the LAL method. |
SDS-PAGE : | 31-35kDa, reducing conditions |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstituteat 100 μg/mL in sterile PBS |
Storage : | Use a manualdefrost freezer and avoid repeated freeze-thaw cycles. 12 months from date ofreceipt, -20 to -70°C as supplied. 1 month, 2 to 8 °C under sterile conditionsafter reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution. |
Gene Name : | FGFBP1 fibroblast growth factorbinding protein 1 [ Homo sapiens ] |
Official Symbol : | FGFBP1 |
Synonyms : | FGFBP1; fibroblastgrowth factor binding protein 1; FGFBP; HBP17; FGF-BP; FGF-BP1; FGFBP-1;FGF-binding protein 1; 17 kDa heparin-binding growth factor-binding protein;17 kDa HBGF-binding protein; heparin-binding growth factor binding protein |
Gene ID : | 9982 |
mRNA Refseq : | NM_005130 |
Protein Refseq : | NP_005121 |
MIM : | 607737 |
UniProt ID : | Q14512 |
Chromosome Location : | 4p15.32 |
Function : | fibroblast growthfactor binding; heparin binding; protein binding |
Products Types
◆ Recombinant Protein | ||
FGFBP1-1994R | Recombinant Rat FGFBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FGFBP1-1524R | Recombinant Rhesus Macaque FGFBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FGFBP1-4118H | Recombinant Human FGFBP1 Protein, GST-tagged | +Inquiry |
FGFBP1-2947H | Recombinant Human FGFBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FGFBP1-53H | Recombinant Human FGFBP1 protein, T7/His-tagged | +Inquiry |
◆ Lysates | ||
FGFBP1-6233HCL | Recombinant Human FGFBP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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