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Active Recombinant Mouse Coxsackie Virus And Adenovirus Receptor

Cat.No. : Cxadr-382M
Product Overview : Recombinantmouse Cxadr protein was expressed in Murine myeloma cellline, NS0-derived. Leu20-Gly237.
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Cat. No. : Cxadr-382M
Description : Cxadr is a 46 kDatype I transmembrane glycoprotein that belongs to the CTX family of the Igsuperfamily. Cxadr has received attention as a receptor that facilitates genetransfer mediated by most adenoviruses. It is also an adhesion moleculewithin junctional complexes, notably between epithelial cells lining bodycavities and within myocardial intercalated discs.
Source : Mammalian cells
Form : Lyophilized from a0.2 μm filtered solution in PBS.
N-terminal Sequence : Leu20
Molecular Weight : 51.2 kDa
Activity : Measured by theability of the immobilized protein to support the adhesion of humanneutrophils. When 2 x 105 cells/well are added to Cxadr coatedplates (10 μg/mL, 100 μL/well), approximately 40-60% of the cells will adhereafter 20 minutes at 37°C.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100 ug/mlin sterile PBS.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution.
Gene Name : Cxadrcoxsackie virus and adenovirus receptor [ Mus musculus ]
Official Symbol : Cxadr
Synonyms : Cxadr; coxsackievirus and adenovirus receptor; CAR; MCAR; MCVADR; AU016810; AW553441;2610206D03Rik; OTTMUSP00000015903; OTTMUSP00000015904; coxsackie virusand adenovirus receptor homolog; Car
Gene ID : 13052
mRNA Refseq : NM_001025192
Protein Refseq : NP_001020363
UniProt ID : P97792
Chromosome Location : 16
Pathway : Adaptive ImmuneSystem; Cell surface interactions at the vascular wall; Hemostasis; ImmuneSystem Immunoregulatory interactions between a Lymphoid and a non-Lymphoidcell Viral; myocarditis
Function : PDZ domain binding;beta-catenin binding; cell adhesion; molecule binding; connexin binding;identical protein binding; protein binding; receptor activity; receptorbinding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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