Active Recombinant Mouse Dickkopf Homolog 1 (Xenopus laevis)
Cat.No. : | Dkk1-398M |
Product Overview : | Recombinant mouse Dkk1protein was expressed in Chinese Hamster Ovary cell line, CHO-derived. Ser30-His272. |
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- Gene Information
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Cat. No. : | Dkk1-398M |
Description : | Dkk1 is the foundingmember of the Dickkopf family of proteins that includes Dkk-1, -2, -3, -4, anda related protein, Soggy. Dkk proteins are secreted proteins that contain twoconserved cysteine-rich domains separated by a linker region. Each domaincontains ten cysteine residues. Mature mouse Dkk1 is a 40 kDa glycosylatedprotein that shares 86%, 96%, 83% and 82% amino acid (aa) sequence identitywith human, rat, rabbit and bovine Dkk1, respectively. |
Source : | Chinese HamsterOvary cell line, CHO-derived |
Form : | Lyophilizedfrom a 0.2 μm filtered solution in PBS with BSA as a carrier protein. |
N-terminal Sequence : | Ser30 & Thr32 |
Molecular Weight : | 26.1 kDa |
Activity : | Measured by itsability to inhibit Wnt-3a-induced alkaline phosphatase production by MC3T3-E1mouse osteoblastic cells. The ND50 for this effect is typically0.02-0.1 μg/mL in the presence of 10 ng/mL of rmWnt-3a. |
Endotoxin Level : | <1.0 EU per 1 μgof the protein by the LAL method. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstitute at 100μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin. |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to-70°C under sterile conditions after reconstitution. |
Gene Name : | Dkk1dickkopf homolog 1 (Xenopus laevis) [ Mus musculus ] |
Official Symbol : | Dkk1 |
Synonyms : | Dkk1; dickkopfhomolog 1; mddk-1; OTTMUSP00000022079; dickkopf-related protein 1; dkk-1; dickkopf-1;mCG_6758 |
Gene ID : | 13380 |
mRNA Refseq : | NM_010051 |
Protein Refseq : | NP_034181 |
UniProt ID : | Q80UL5 |
Chromosome Location : | 19 |
Pathway : | Wnt SignalingPathway; PluriNetWork |
Function : | Low-density lipoprotein particle binding; receptorantagonist activity; protein binding |
Products Types
◆ Recombinant Protein | ||
DKK1-195H | Recombinant Human DKK1 Protein, Fc-tagged | +Inquiry |
Dkk1-293D | Active Recombinant Mouse Dkk1 Protein (243 aa) | +Inquiry |
Dkk1-197M | Recombinant Mouse Dkk1 Protein, His-tagged | +Inquiry |
Dkk1-1534R | Recombinant Rat Dkk1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DKK1-1267H | Acitve Recombinant Human DKK1 protein(Met2-His266), hFc-tagged | +Inquiry |
◆ Lysates | ||
DKK1-2983HCL | Recombinant Human DKK1 cell lysate | +Inquiry |
DKK1-2622RCL | Recombinant Rhesus DKK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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