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Recombinant Human CD274 Molecule, His-tagged

Cat.No. : CD274-6775H
Product Overview : Recombinant humanCD274 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography.
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Cat. No. : CD274-6775H
Description : CD274, also known asprogrammed cell death 1 ligand 1(PDCD1L1), is involved in the costimulatorysignal, essential for T-cell proliferation and production of IL10 and IFNG,in an IL2-dependent and a PDCD1-independent manner. This protein interactionwith PDCD1 inhibits T-cell proliferation and cytokine production.
Form : Liquid. 20mMTris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT
Molecular Weight : 27.9 kDa (245aa),confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Purity : > 90% by SDS -PAGE
Concentration : 1 mg/ml (determinedby Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSHMFTVTV PKDLYVVEYG SNMTIECKFP VEKQLDLAAL IVYWEMEDKN IIQFVHGEEDLKVQHSSYRQ RARLLKDQLS LGNAALQITD VKLQDAGVYR CMISYGGADY KRITVKVNAP YNKINQRILVVDPVTSEHEL TCQAEGYPKA EVIWTSSDHQ VLSGKTTTTN SKREEKLFNV TSTLRINTTT NEIFYCTFRRLDPEENHTAE LVIPELPLAH PPNER
Storage : Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : CD274CD274 molecule [ Homo sapiens ]
Official symbol : CD274
Synonyms : CD274; CD274 molecule; B7-H; B7H1;PDL1; PD-L1; PDCD1L1; PDCD1LG1; MGC142294; MGC142296; programmed cell death 1ligand 1; CD274 antigen; Programmed cell death 1 ligand 1; Programmed deathligand 1; PDCD1 ligand 1; B7 homolog 1; OTTHUMP00000021029
Gene ID : 29126
mRNA Refseq : NM_014143
Protein Refseq : NP_054862
MIM : 605402
UniProt ID : Q9NZQ7
Chromosome Location : 9q24.1
Pathway : Cell adhesion molecules (CAMs);Signaling in Immune system
Function : protein binding; receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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