Recombinant Human Nucleophosmin (nucleolar phosphoprotein B23, numatrin), His-tagged
Cat.No. : | NPM1-6799H |
Product Overview : | Recombinant humanNPM1 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NPM1-6799H |
Description : | NPM1 is aphosphoprotein which moves between the nucleus and the cytoplasm. It isthought to be involved in several processes including regulation of theARF/p53 pathway. A number of genes are fusion partners have beencharacterized, in particular the anaplastic lymphoma kinase gene onchromosome 2. Mutations in NPM1 are associated with acute myeloid leukemia |
Form : | Liquid. 20mMTris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl,1mM DTT |
Molecular Weight : | 34.7kDa (314aa),confirmed by MALDI-TOF |
Purity : | > 85% by SDS -PAGE |
Concentration : | 0.5 mg/ml(determined by Bradford assay) |
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIVEAEAMNYEGSPIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE EDAESEDEEEEDVKLLSISG KRSAPGGGSK VPQKKVKLAADEDDDDDDEE DDDEDDDDDD FDDEEAEEKA PVKKSIRDTPAKNAQKSNQN GKDSKPSSTP RSKGQESFKK QEKTPKTPKG PSSVEDIKAKMQASIEKGGS LPKVEAKFINYVKNCFRMTD QEAIQDLWQW RKSL |
Storage : | Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | aurora B signaling; BARD1 signalingevents; chromosome Maintenance; deposition of New CENPA-containingNucleosomes at the Centromere; HIF-1-alpha transcription factor network; HIVInfection; host Interactions of HIV factors; interactions of Rev with hostcellular proteins; nuclear import of Rev protein; nucleosome assembly;validated targets of C-MYC transcriptional activation |
Gene Name : | NPM1 nucleophosmin (nucleolarphosphoprotein B23, numatrin) [ Homo sapiens ] |
Official Symbol : | NPM1 |
Synonyms : | NPM1; nucleophosmin (nucleolarphosphoprotein B23, numatrin); B23; NPM; MGC104254; nucleophosmin; numatrin;OTTHUMP00000161024; OTTHUMP00000161025; OTTHUMP00000223397; OTTHUMP00000223398;nucleolar protein NO38; nucleophosmin/nucleoplasmin family, member 1 |
Gene ID : | 4869 |
mRNA Refseq : | NM_199185 |
Protein Refseq : | NP_954654 |
MIM : | 164040 |
UniProt ID : | P06748 |
Chromosome Location : | 5q35.1 |
Function : | NF-kappaB binding; RNA binding; Tatprotein binding; histone binding; protein binding; protein heterodimerizationactivity; ribosomal large subunit binding; transcription coactivatoractivity; unfolded protein binding |
Products Types
◆ Recombinant Protein | ||
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NPM1-3705R | Recombinant Rat NPM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Npm1-4474M | Recombinant Mouse Npm1 Protein, Myc/DDK-tagged | +Inquiry |
NPM1-3805H | Recombinant Human NPM1 protein(Met9-Leu158), His-tagged | +Inquiry |
NPM1-2572H | Recombinant Human NPM1 protein(21-130 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
NPM1-3738HCL | Recombinant Human NPM1 293 Cell Lysate | +Inquiry |
NPM1-3737HCL | Recombinant Human NPM1 293 Cell Lysate | +Inquiry |
NPM1-3739HCL | Recombinant Human NPM1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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