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Recombinant Human Tyrosyl-tRNA Synthetase 2, Mitochondrial, His-tagged

Cat.No. : YARS2-6783H
Product Overview : Recombinant humanYARS2 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography
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  • Gene Information
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Cat. No. : YARS2-6783H
Description : YARS2, also known astyrosyl-tRNA synthetase, catalyzes the attachment of tyrosine to tRNA(Tyr) ina two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP andthen transferred to the acceptor end of tRNA(Tyr)
Form : Liquid. 20mMTris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Molecular Weight : 53.7 kDa (482aa)
Purity : > 85% by SDS -PAGE
Concentration : 0.25 mg/ml(determined by Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MTLNLSVLLP LGLRKAHSGA QGLLAAQKAR GLFKDFFPET GTKIELPELF DRGTASFPQTIYCGFDPTAD SLHVGHLLAL LGLFHLQRAG HNVIALVGGA TARLGDPSGR TKEREALETE RVRANARALRLGLEALAANH QQLFTDGRSW GSFTVLDNSA WYQKQHLVDF LAAVGGHFRM GTLLSRQSVQ LRLKSPEGMSLAEFFYQVLQ AYDFYYLFQR YGCRVQLGGS DQLGNIMSGY EFINKLTGED VFGITVPLIT STTGAKLGKSAGNAVWLNRD KTSPFELYQF FVRQPDDSVE RYLKLFTFLP LPEIDHIMQL HVKEPERRGP QKRLAAEVTKLVHGREGLDS AKRCTQALYH SSIDALEVMS DQELKELFKE APFSEFFLDP GTSVLDTCRK ANAIPDGPRGYRMITEGGVS INHQQVTNPE SVLIVGQHIL KNGLSLLKIG KRNFYIIKWL QL
Storage : Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : YARS2tyrosyl-tRNA synthetase 2, mitochondrial [ Homo sapiens ]
Official Symbol : YARS2
Synonyms : YARS2; tyrosyl-tRNA synthetase 2,mitochondrial; tyrosyl-tRNA synthetase, mitochondrial; CGI 04; FLJ13995; mtTyrRS; tyrosine tRNA ligase 2; mitochondrial; CGI 04; FLJ13995; mt TyrRS;Tyrosine tRNA ligase; Tyrosyl tRNA synthetase 2, mitochondrial; TYRRS; YARS2; tyrosine tRNA ligase 2, mitochondrial; TYRRS; CGI-04; MLASA2; MT-TYRRS
Gene ID : 51067
mRNA Refseq : NM_001040436
Protein Refseq : NP_001035526
MIM : 610957
Uniprot ID : Q9Y2Z4
Chromosome Location : 12p11.21
Pathway : Aminoacyl-tRNA biosynthesis,organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conservedbiosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specificbiosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; GeneExpression, organism-specific biosystem
Function : ATP binding; ligase activity;nucleotide binding; protein homodimerization activity; tRNA binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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