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Recombinant Human Ubiquitin-Conjugating Enzyme E2H, His-tagged

Cat.No. : UBE2H-1959H
Product Overview : Recombinant humanUBE2H protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.
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  • Gene Information
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Cat. No. : UBE2H-1959H
Description : UBE2H(Ubiquitin-conjugating enzyme E2 H) belongs to the ubiquitin-conjugatingenzyme family. The modification of proteins with ubiquitin is an importantcellular mechanism for targeting abnormal or short-lived proteins fordegradation. Ubiquitination involves at least three classes of enzymes:ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s,and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2ubiquitin-conjugating enzyme family. UBE2H is Accepts ubiquitin from the E1complex and catalyzes its covalent attachment to other proteins.
Form : Liquid. In 20 mMTris-HCl buffer, pH8.0, 10% glycerol, 1mM DTT, 50mM NaCl.
Molecular Weight : 23.1 kDa(206aa) confirmed by MALDI-TOF.
Purity : > 95%by SDS-PAGE
Concentration : 1 mg/ml(determined by Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSMSSPSPG KRRMDTDVVK LIESKHEVTI LGGLNEFVVK FYGPQGTPYEGGVWKVRVDL PDKYPFKSPS IGFMNKIFHP NIDEASGTVC LDVINQTWTA LYDLTNIFES FLPQLLAYPNPIDPLNGDAA AMYLHRPEEY KQKIKEYIQK YATEEALKEQ EEGTGDSSSE SSMSDFSEDE AQDMEL
Storage : Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : UBE2H ubiquitin-conjugatingenzyme E2H [ Homo sapiens ]
Official Symbol : UBE2H
Synonyms : UBE2H; ubiquitin-conjugating enzyme E2H;UBC8; UbcH2; UBCH; UBCH2; E2-20K; ubiquitin-conjugating enzyme E2 H;ubiquitin-protein ligase H; ubiquitin carrier protein H;ubiquitin-conjugating enzyme E2-20K; ubiquitin-conjugating enzyme E2H (UBC8homolog, yeast); ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8);EC 6.3.2.19; OTTHUMP00000212335; OTTHUMP00000212338; OTTHUMP00000212339;OTTHUMP00000212355
Gene ID : 7328
mRNA Refseq : NM_003344
Protein Refseq : NP_003335
MIM : 601082
UniProt ID : P62256
Chromosome Location : 7q32
Pathway : Adaptive Immune System; Antigen processing;Class I MHC mediated antigen processing & presentation; Immune System;Ubiquitin mediated proteolysis
Function : ATP binding; acid-amino acid ligaseactivity; ligase activity; nucleotide binding; ubiquitin-protein ligaseactivity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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