Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Antibody > Monoclonal Antibodies > Mouse Anti-Human TPMT Monoclonal Antibody

Mouse Anti-Human TPMT Monoclonal Antibody

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Human(12)
Mouse(5)
Rat(3)
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GST(1)
His(1)
N/A(2)
Cat. No.:
CAB-11471MH
Product Overview:
Anti-human TPMT mAb,is derived from hybridization of mouse F0 myeloma cells with spleen cellsfrom BALB/c mice immunized with a recombinant human TPMT protein.
Antigen Description:
TPMT (ThiopurineS-methyltransferase) is a very important enzyme for the metabolizm ofthiopurine compounds. TPMT pharmacogenetics has been studied extensivelybecause of its clinical significance. Many patients got benefited from theknowledge of TPMT genotype-phenotype correlation. Also, TPMT activityexhibits autosomal codominant genetic polymorphism, and patients inheritingTPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity.
Immunogen:
Recombinant humanTPMT (1-245aa) purified from E. coli.
Host:
Mouse
Isotype:
Mouse IgG1heavy chain and κ light chain.
Application:
ELISA; WB
Clone:
BU3F8
Description:
TPMT isan enzyme that methylates thiopurine compounds. The methyl donor isS-adenosyl-L-methionine, which is converted to S-adenosyl-L-homocysteine.
Concentration:
1 mg/ml
Form:
Liquid.In Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
Usage:
Theantibody has been tested by ELISA, Western blot analysis to assurespecificity and reactivity. Since application varies, however, eachinvestigation should be titrated by the reagent to obtain optimal results.Recommended dilution range for Western blot analysis is 1:1000.
Storage:
Can bestored at +4°C. For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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