Recombinant Human HTR2A, His-tagged
Cat.No. : | HTR2A-1561H |
Product Overview : | Recombinant Human HTR2A encoding human5-hydroxytryptamine receptor 2A (a.a.1–471) was fused a His-tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HTR2A-1561H |
Description : | This gene encodes one of the receptors for serotonin, aneurotransmitter with many roles. Mutations in this gene are associated withsusceptibility to schizophrenia and obsessive-compulsive disorder, and arealso associated with response to the antidepressant citalopram in patientswith major depressive disorder (MDD). MDD patients who also have a mutationin intron 2 of this gene show a significantly reduced response to citalopramas this antidepressant downregulates expression of this gene. Multipletranscript variants encoding different isoforms have been found for thisgene. |
Applications : | Western Blot; ELISA |
Purity : | >90%, as determined by SDS-PAGE under reducingconditions |
Formulation : | Liquid |
Storage : | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoidrepeated freeze-thaw |
Gene Name : | HTR2A 5-hydroxytryptamine(serotonin) receptor 2A, G protein-coupled [ Homo sapiens ] |
Official Symbol : | HTR2A |
Synonyms : | HTR2; 5-HT2A; 5-hydroxytryptaminereceptor 2A; 5-HT-2A; 5-HT2 receptor; serotonin 5-HT-2A receptor |
Gene ID : | 3356 |
mRNA Refseq : | NM_000621 |
Protein Refseq : | NP_000612 |
MIM : | 182135 |
UniProt ID : | P78352 |
Chromosome Location : | 13q14-q21 |
Pathway : | Amine ligand-binding receptors; Calciumsignaling pathway; GPCR downstream signaling |
Function : | drug binding; receptoractivity |
Products Types
◆ Recombinant Protein | ||
HTR2A-3131H | Recombinant Human HTR2A Protein, His (Fc)-Avi-tagged | +Inquiry |
HTR2A-1996R | Recombinant Rhesus Macaque HTR2A Protein, His (Fc)-Avi-tagged | +Inquiry |
HTR2A-4374M | Recombinant Mouse HTR2A Protein, His (Fc)-Avi-tagged | +Inquiry |
HTR2A-2617R | Recombinant Rat HTR2A Protein, His (Fc)-Avi-tagged | +Inquiry |
HTR2A-1729H | Recombinant Human HTR2A, His-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1352 | HTR2A U2OS β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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