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Recombinant Human HDAC6 protein, FLAG-tagged

Cat.No. : HDAC6-400H
Product Overview : Recombinant human HDAC6 was expressed in a baculovirus expression system as the full length protein (accession number NP_001308154.1) with a C-terminal FLAG-Tag. The molecular weight of the protein is 135.7 kDa. The recombinant protein is >85% pure by SDS-PAGE.
  • Specification
  • Gene Information
  • Related Products
Source : Insect cell
Species : Human
Tag : FLAG
Form : 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100, 0.5 mM TCEP.
Molecular Mass : 135.7 kDa
Purity : >85%
Applications : Recombinant HDAC6 protein is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage : Recombinant proteins in solution are temperature sensitive and must be stored at -80 centigrade to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Expiry : 6 months
Concentration : 0.3 μg/μl
Gene Name : HDAC6 histone deacetylase 6 [ Homo sapiens (human) ]
Official Symbol : HDAC6
Synonyms : Histone Deacetylase 6; HDAC-6; HD6
Gene ID : 10013
mRNA Refseq : NM_006044
Protein Refseq : NP_006035
MIM : 300272
UniProt ID : Q9UBN7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can HDAC6 inhibitors be used in combination with other therapies, and if so, what synergistic effects are expected? 06/19/2022

Yes, HDAC6 inhibitors can be combined with other therapies for enhanced efficacy. Synergistic effects may include improved anti-cancer activity or neuroprotection.

Are there any ongoing clinical trials targeting HDAC6, and if so, what are the potential outcomes for patients? 05/29/2020

Yes, there are clinical trials exploring HDAC6 inhibitors as potential treatments. Positive outcomes could lead to new therapeutic options for patients.

In what other diseases has HDAC6 been implicated, and how might this knowledge be applied clinically? 12/24/2018

HDAC6 is implicated in neurodegenerative diseases and inflammatory disorders. Understanding its role could lead to novel therapeutic approaches for these conditions.

How does HDAC6 influence cellular processes, and why is this relevant in a clinical setting? 12/13/2017

HDAC6 regulates cell motility, protein trafficking, and other processes. Understanding these mechanisms is crucial for developing targeted therapies in various diseases.

Are there any known genetic variations in HDAC6, and how might these impact individual responses to treatments in a clinical setting? 08/22/2016

Genetic variations in HDAC6 may influence individual responses to treatments. Personalized medicine approaches could consider these variations for better outcomes.

Customer Reviews (3)

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Reviews
06/23/2019

    Their expertise and guidance have helped overcome hurdles, ensuring the smooth progress of my research.

    12/07/2018

      The bands of proteins in Western Blotting experiments were very clear.

      09/16/2018

        Its purity and consistency have provided me with reliable and reproducible results, ensuring the accuracy of my research findings.

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