Recombinant Human Akt3, GST-tagged

• Cat.No.: Akt3-162H
• Product Overview: Recombinant HumanAkt3 fused with a GST tag was produced in E.coli and purified byGSH-sepharose.

Specification

• Cat. No.: Akt3-162H
• Description: The protein encoded by this gene is a member of theAKT, also called PKB, serine/threonine protein kinase family. AKT kinases areknown to be regulators of cell signaling in response to insulin and growthfactors. They are involved in a wide variety of biological processesincluding cell proliferation, differentiation, apoptosis, tumorigenesis, aswell as glycogen synthesis and glucose uptake. This kinase has been shown tobe stimulated by platelet-derived growth factor (PDGF), insulin, andinsulin-like growth factor 1 (IGF1). Alternatively splice transcript variantsencoding distinct isoforms have been described.
• Source: E. coli.
• Species: Human
• Antigenpeptide region: 95-155aa
• StorageBuffer: 1MPBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1%Triton X-100,15%glycerol.
• Storage: Theprotein is stored in PBSbuffer at -20 °C.Repeated freezethaw cycles should be avoided.
• OfficialSymbol: AKT3

Gene Information

• Gene Name: AKT3 v-akt murine thymomaviral oncogene homolog 3 (protein kinase B, gamma) [ Homo sapiens ]
• Synonyms: AKT3; v-akt murinethymoma viral oncogene homolog 3 (protein kinase B, gamma); PKBG; PRKBG;STK-2; PKB-GAMMA; RAC-gamma; RAC-PK-gamma; DKFZp434N0250; RAC-gammaserine/threonine-protein kinase; PKB gamma; EC 2.7.11.1; Protein kinase Akt-3;Protein kinase B gamma; OTTHUMP00000037911; OTTHUMP00000037912; serinethreonine protein kinase, Akt-3; EC 2.7.11
• Gene ID: 10000
• mRNA Refseq: NM_001206729
• Protein Refseq: NP_001193658
• MIM: 611223
• UniProt ID: Q9Y243
• Chromosome Location: 1q44
• Pathway: Acutemyeloid leukemia; Adaptive Immune System; Apoptosis
• Function: ATPbinding; nucleotide binding; protein binding