Recombinant Human ASGR1, His-tagged
Cat.No. : | ASGR1-589H |
Product Overview : | Recombinant human ASGR1 with apolyhistidine tag at the N-terminus was expressed in Human Cells, 28.8 kDa (246aa). |
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Cat. No. : | ASGR1-589H |
Description : | This geneencodes a subunit of the asialoglycoprotein receptor. This receptor is atransmembrane protein that plays a critical role in serum glycoproteinhomeostasis by mediating the endocytosis and lysosomal degradation ofglycoproteins with exposed terminal galactose or N-acetylgalactosamineresidues. The asialoglycoprotein receptor may facilitate hepatic infection bymultiple viruses including hepatitis B, and is also a target forliver-specific drug delivery. The asialoglycoprotein receptor is ahetero-oligomeric protein composed of major and minor subunits, which areencoded by different genes. The protein encoded by this gene is the moreabundant major subunit. Alternatively spliced transcript variants encodingmultiple isoforms have been observed for this gene. |
Source : | HumanCells |
Species : | Human |
Purity : | >90 % as determined by SDS-PAGE. |
Endotoxin : | <1.0 EU per μg of the protein as determined by the LAL method. |
Stability : | Samplesare stable for up to twelve months from date of receipt at -70 °C. |
Predicted N terminal : | His |
Formulation : | Lyophilizedfrom 0.2 μm filtered solution of. Normally 5 % - 8 % trehalose and mannitolare added as protectants before lyophilization. |
Storage : | Storeit under sterile conditions at -70 °C.It is recommended that the protein be aliquoted for optimal storage. Avoidrepeated freeze-thaw cycles. |
OfficialSymbol : | ASGR1 |
Gene Name : | ASGR1 asialoglycoprotein receptor1 [ Homo sapiens ] |
Synonyms : | ASGR1;asialoglycoprotein receptor 1; HL-1; ASGPR; ASGPR1; CLEC4H1; hepatic lectinH1; C-type lectin domain family 4 member H1; OTTHUMP00000128354; ASGP-R 1 |
Gene ID : | 432 |
mRNA Refseq : | NM_001197216 |
Protein Refseq : | NP_001184145 |
MIM : | 108360 |
UniProt ID : | P07306 |
Chromosome Location : | 17p13.2 |
Function : | asialoglycoproteinreceptor activity; metal ion binding; protein binding |
Products Types
◆ Recombinant Protein | ||
ASGR1-0667H | Recombinant Human ASGR1 Protein (T2-L291), His tagged | +Inquiry |
ASGR1-388H | Recombinant Human ASGR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ASGR1-2580H | Recombinant Human ASGR1 protein(71-150 aa), C-hFc & C-His-tagged | +Inquiry |
ASGR1-476R | Recombinant Rat ASGR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Asgr1-656M | Recombinant Mouse Asgr1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
ASGR1-1601HCL | Recombinant Human ASGR1 cell lysate | +Inquiry |
ASGR1-3084MCL | Recombinant Mouse ASGR1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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