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Recombinant Human NME4, His-tagged

Cat.No. : NME4-795H
Product Overview : Recombinant human NME4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography (33-187aa).
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Cat. No. : NME4-795H
Description : NME4, also known as nucleoside diphosphate kinase, mitochondrial, belongs to the NDK family. NME4 are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. The enzymes are products of the nm23 gene family, which includes NME4. NME4 plays a major role in the synthesis of nucleoside triphosphates other than ATP.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.2M NaCl
Molecular Weight : 19.6 kDa (176aa) confirmed by MALDI-TOF
Purity : > 90% by SDS - PAGE
Concentration : 0.5 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MPSWTRERTL VAVKPDGVQR RLVGDVIQRF ERRGFTLVGM KMLQAPESVL AEHYQDLRRK PFYPALIRYMSSGPVVAMVW EGYNVVRASR AMIGHTDSAE AAPGTIRGDF SVHISRNVIH ASDSVEGAQR EIQLWFQSSE LVSWADGGQH SSIHPA
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Gene Name : NME4 non-metastatic cells 4, protein expressed in[ Homo sapiens ]
Synonyms : NME4; NDPK-D; NM23H4; nm23-H4; nucleoside diphosphate kinase, mitochondrial; NDK; nucleoside diphosphate kinase D; NDPKD;NDP kinase D; OTTHUMP00000194917; OTTHUMP00000194919; OTTHUMP00000206530; NDP kinase, mitochondrial; NP_005000.1; EC 2.7.4.6
Gene ID : 4833
mRNA Refseq : NM_005009
Protein Refseq : NP_005000
MIM : 601818
UniProt ID : O00746
Chromosome Location : 16p13.3
Function : ATP binding; kinase activity; metal ion binding; nucleoside diphosphate kinase activity; nucleotide binding; transferase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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