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Cat. No.
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MOM18002
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ProductOverview
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Recombinant monoclonalantibody to Human TAG72
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Antigendescription
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The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.
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CASnumber
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138955-26-7
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Type
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IgG
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Formulation
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Normally 1mg/mlL-His, 1mg/ml Sucrose and 0.04 mg/ml Tween-80 are added, pH 6.0. Pleasecontact us for any concerns or special requirements.
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Purity Detail
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>95% asdetermined by SDS-PAGE and HPLC
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Expression Host
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Chinese HamsterOvary (CHO cell)
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Molecular Mass
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141478.9
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Predicted N terminal
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H Chain: QVQLQQS
L Chain: DIQMTQS
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Storage
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Store it understerile conditions at -70oC upon receiving.Recommend to pack the protein into smaller quantities for optimal storage.
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Activity/Specificity
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Tested positive against native human antigen
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Application
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Suitable for use in ELISA, western blot, immunohistochemistry, flow cytometry, immunoaffinity purification and most other immunological methods.
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Background
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This monoclonal antibodycan be attached to the chelatorpentetic acid (DTPA) linked to the tripeptide glycine (G) – L-tyrosine (Y) – L-lysine (K), which chelates Indium 111 and binds selectively to cell-surface TAG-72 expressed on colorectal tumors.
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Synonyms
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CA 72.4; TAG 72; Tumor associated Glycoprotein 72 antibody
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Download Datasheet:
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