"ADAM12" Related Products

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Mouse Anti-Human ADAM Metallopeptidase Domain 12 Monoclonal Antibody

Cat. No.: CABT-676MH
Product Overview: Mouse Anti-Human ADAM metallopeptidase domain 12 Monoclonal Antibody.
Antigen Dscription: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.
Host Animal: Mouse
Species Reactivity: Human
Immunogen: A recombinant polypeptide corresponding to amino acids 208-305 of human ADAM12, expressed as a GST fusion protein.
Clone: 2H4
Isotype: IgG3
Format: Purified
Presentation: Liquid; In PBS, pH 7.2, containing no preservative.
Applications: ELISA (this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 μg/well, 100 μl total volume. Variables associated with assay conditions will dictate the proper working dilution); Immunoblotting (1-5 μg/ml).
Storage: Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.
Officialsymbol: ADAM12
Gene Name: ADAM12 ADAM metallopeptidase domain 12 [ Homo sapiens ]
Synonyms: ADAM12; ADAM metallopeptidase domain 12; MCMP; MCMPMltna; MLTN; MLTNA; A Disintegrin and Metalloprotease Domain 12 S isoform; ADAM12 precursor (EC 3.4.24); Meltrin alpha; ADAM12 ADAM metallopeptidase domain 12; OTTHUMP00000020727; OTTHUMP00000046766; a disintegrin and metalloproteinase domain 12 (meltrin alpha); EC 3.4.24.; A disintegrin and metalloproteinase domain 12
Gene ID: 8038
mRNA Refseq: NM_003474
Protein Refseq: NP_003465
MIM: 602714
UniProt ID: O43184
Chromosome Location: 10q26.3
Pathway: Signaling by EGFR
Function: SH3 domain binding; metal ion binding ; metalloendopeptidase activity; peptidase activity; protein binding; zinc ion binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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