Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Antibody > Polyclonal Antibody > Rabbit Anti-Human ADAM Metallopeptidase Domain 12 Polyclonal Antibody

Rabbit Anti-Human ADAM Metallopeptidase Domain 12 Polyclonal Antibody

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"ADAM12" Related Products.
By Species
Chicken(2)
Human(10)
Mouse(3)
By Source
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By Tag
His(7)
N/A(3)
Cat. No.:
CPBT-676RH
Product Overview:
Rabbit Anti-Human ADAM metallopeptidase domain 12 Polyclonal Antibody.
Antigen Dscription:
ADAM12, also named as MLTN and Meltrin-alpha, is involved in skeletal muscle regeneration, specifically at the onset of cell fusion. It is also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. ADAM12 is expressed in human malignant tumors. It is involved in the regulation of growth factor activities and integrin functions, leading to promotion of cell growth and invasion, although the precise mechanisms of these are not clear at the present time.(PMID:17355265) ADAM12's ability to degrade extracellular matrix components likely allows it to detach cancer cells from the basement membrane and assist them on their route to metastasis. But the protein's role not just as a biomarker of breast cancer but as a gateway to cancer cell migration is only now being understood.
Host Animal:
Rabbit
Species Reactivity:
Human
Immunogen:
Human ADAM12 gst fusion protein
Isotype:
IgG
Purification:
Antigen Affinity purified
Caculated Molecular Weight:
100kd
Observed Molecular Weight:
97kd,68kd
Applications:
ELISA, WB, IHC, IF
Storage:
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 oC, Avoid freeze / thaw cycles.
Officialsymbol:
ADAM12


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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