Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Cell Division Cycle Associated 8, His-tagged

Cat.No. : CDCA8-3526H
Product Overview : Recombinant human CDCA8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (19-280aa).
  • Specification
  • Gene Information
  • Related Products
Cat. No. : CDCA8-3526H
Description : CDCA8, also known as Borealin, is a component of the chromosomal passenger complex (CPC). The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.In the complex, CDCA8 protein may be required to direct the CPC to centromeric DNA. Deletion of CDCA8 delays mitotic progression and causes kinetochore-spindle to mis-attach.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,50% glycerol, 1mM EDTA, 0.2M NaCl
Molecular Weight : 31.6 kDa (283aa)confirmed by MALDI-TOF
Purity : > 90% by SDS - PAGE
Concentration : 0.25 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MRKLASFLKD FDREVEIRIK QIESDRQNLL KEVDNLYNIE ILRLPKALRE MNWLDYFALG GNKQALEEAATADLDITEIN KLTAEAIQTP LKSAKTRKVI QVDEMIVEEE EEEENERKNL QTARVKRCPP SKKRTQSIQG KGKGKRSSRA NTVTPAVGRLEVSMVKPTPG LTPRFDSRVF KTPGLRTPAA GERIYNISGN GSPLADSKEI FLTVPVGGGE SLRLLASDLQ RHSIAQLDPE ALGNIKKLSNRLAQICSSIR THK
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Gene Name : CDCA8 cell division cycle associated 8 [ Homo sapiens ]
Synonyms : CDCA8; BOR; DasraB; MESRGP; BOREALIN; FLJ10468; FLJ12042; borealin; Dasra B; dasra-B; hDasra-B; OTTHUMP00000004514; cell division cycle-associated protein 8; pluripotent embryonic stem cell-related gene 3 protein
Gene ID : 55143
mRNA Refseq : NM_018101
Protein Refseq : NP_060571
MIM : 609977
UniProt ID : Q53HL2
Chromosome Location : 1p34.3
Function : protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All CDCA8 Products

Required fields are marked with *

My Review for All CDCA8 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends