Rabbit Anti-Human VEGF-D Monoclonal Antibody
Cat.No. : | CAB11546RH |
Product Overview : | Rabbit Monoclonal Antibody to Human VEGF-D |
- Specification
- Gene Information
- Related Products
Antigen Description : | Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), is a vascular endothelial growth factor. This secreted protein is a member of the platelet derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and performs activities in angiogenesis, lymphangiogenesis, and endothelial cell growth. Human VEGF-D is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. It is structurally and functionally similar to VEGF-C, and is secreted as a non-covelent homodimer in a antiparallel fashion. VEGF-D undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. Like VEGFC, it may particularly be involed in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. |
Specificity : | Human VEGF-D / FIGF / VEGFD. No cross-reactivity in ELISA with human VEGF-C / Flt4-Land human cell lysate (293 cell line) |
Immunogen : | Recombinant human VEGF-D protein |
Host : | Rabbit |
Isotype : | Rabbit IgG |
Species : | Human |
Cross Reactivity : | 201 |
Clone : | A202 |
Applications : | WB; ELISA |
Dilution : | Western blot: This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect human VEGF-D in WB. Using a DAB detection system, the detection limit for human VEGF-D is approximately 0.5 ng/lane under non-reducing conditions and 50 ng/lane under reducing conditionsELISA: This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human VEGF-D. The detection limit for human VEGF-Dis approximately 0.0049 ng/well |
Preparation : | This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human VEGF-D. |
Format : | 0.2 μm filtered solution in PBS with 5% trehalose |
Storage : | This antibody can be stored at 2-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 to -70 °C. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Gene Name : | FIGF c-fos induced growth factor (vascular endothelial growth factor D) [ Homo sapiens ] |
Official Symbol : | FIGF |
Synonyms : | FIGF; c-fos induced growth factor (vascular endothelial growth factor D); VEGFD; vascular endothelial growth factor D; VEGF D; VEGF-D; |
Gene ID : | 2277 |
mRNA Refseq : | NM_004469 |
Protein Refseq : | NP_004460 |
MIM : | 300091 |
UniProt ID : | O43915 |
Chromosome Location : | Xp22.31 |
Pathway : | Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; |
Function : | chemoattractant activity; growth factor activity; platelet-derived growth factor receptor binding; protein homodimerization activity; vascular endothelial growth factor receptor 3 binding; vascular endothelial growth factor receptor binding; |
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FIGF-2005R | Recombinant Rat FIGF Protein, His (Fc)-Avi-tagged | +Inquiry |
FIGF-301286H | Recombinant Human FIGF protein, GST-tagged | +Inquiry |
FIGF-167H | Active Recombinant Human FIGF | +Inquiry |
FIGF-3727Z | Recombinant Zebrafish FIGF | +Inquiry |
◆ Lysates | ||
FIGF-1312MCL | Recombinant Mouse FIGF cell lysate | +Inquiry |
FIGF-2767HCL | Recombinant Human FIGF cell lysate | +Inquiry |
FIGF-1265RCL | Recombinant Rat FIGF cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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