|
Cat. No.
|
MOM-18001-S(P)
|
|
ProductOverview
|
Affinity-purified monoclonal antibody fragments scFv(single chain variablefragments) expressed in E. coli to bind against human CD20.
|
|
Antigendescription
|
CD20 is B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells.
|
|
Immunogen
|
Human lymphoblastoid cell line SB
|
|
Isotype
|
Mouse IgG1κscFv
|
|
Formulation
|
Normally 1mg/mlL-His, 1mg/ml Sucrose and 0.04 mg/ml Tween-80 are added, pH 6.0. Pleasecontact us for any concerns or special requirements.
|
|
Purity Detail
|
>95% asdetermined by SDS-PAGE and HPLC
|
|
Expression Host
|
E. coli
|
|
Stability
|
Samples are stable for up to twelve months from date of receipt at -20ºC and are stable for six months at 4ºC.
|
|
Storage
|
Store it understerile conditions at -20ºC upon receiving.Recommend to pack the protein into smaller quantities for optimal storage.
|
|
Activity/Specificity
|
Tested positive against native human antigen
|
|
Application
|
Suitable for use in ELISA, western blot, immunohistochemistry, flow cytometry, immunoaffinity purification and most other immunological methods.
|
|
Background
|
Anti-CD20 monoclonal Antibodyis a monoclonal antibody used in radioimmunotherapy treatment for some forms of B cellnon-Hodgkin"s lymphoma, a lymphoproliferative disorder and thus affects the lymphatic system.
|
|
AntigenGene Information
|
|
Gene Name
|
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 [ Homo sapiens ]
|
|
Official Symbol
|
MS4A1
|
|
Synonyms
|
B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; MGC3969; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1; APY;ATOPY; B lymphocyte antigen CD20; B Lymphocyte Cell Surface Antigen B1; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; FCERI
|
|
GeneID
|
931
|
|
mRNARefseq
|
NM_152866.2
|
|
ProteinRefseq
|
NP_690605.1
|
|
MIM
|
112210
|
|
UniProtID
|
P11836
|
|
ChromosomeLocation
|
11q12
|
|
Pathway
|
Hematopoietic cell lineage
|
|
Function
|
Epidermal growth factor receptor binding
|
|
|
|
Download Datasheet:
|
|