Recombinant Human CD74, GST-Tagged
Cat.No. : | CD74-2230H |
Product Overview : | Recombinant Human CD74 encoding full-length human CD74 ( 1a.a. - 160 a.a.) , fused a GST-tag at N-terminal, was expressed in Wheat germ. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CD74-2230H |
Description : | The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
Sequence : | MHRRRSRSCREDQKPVMDDQRDLIS NNEQLPMLGRRPGAPESKCSRGALY TGFSILVTLLLAGQATTAYFLYQQQ GRLDKLTVTSQNLQLENLRMKLPKP PKPVSKMRMATPLLMQALPMGALPQ GPMQNATKYGNMTEDHVMHLLQSHW NWRTRLLGWV |
MW (kDa) : | 43.34 |
Preparation Method : | in vitro wheat germ expression system |
Purification : | Glutathione Sepharose 4 Fast Flow |
Applications : | Antibody Production; Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Protein Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | CD74 CD74 molecule, major histocompatibility complex, class II invariant chain [ Homo sapiens ] |
Official Symbol : | CD74 |
Synonyms : | CD74 molecule, major histocompatibility complex, class II invariant chain; DHLAG; HLADG; Ia-GAMMA; CD74; HLA class II histocompatibility antigen gamma chain; ii; p33; HLA-DR-gamma; MHC HLA-DR gamma chain; Ia-associated invariant chain; gamma chain of class II antigens; ia antigen-associated invariant chain; HLA-DR antigens-associated invariant chain; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 antigen |
Gene ID : | 972 |
mRNA Refseq : | NM_004355 |
Protein Refseq : | NP_004346 |
MIM : | 142790 |
UniProt ID : | P04233 |
Chromosome Location : | 5q32 |
Pathway : | Antigen processing and presentation |
Function : | MHC class II protein binding; beta-amyloid binding; cytokine binding; cytokine receptor activity; identical protein binding |
Products Types
◆ Recombinant Protein | ||
CD74-698H | Recombinant Human CD74 Protein, His-tagged | +Inquiry |
Cd74-1231M | Recombinant Mouse Cd74 Protein, MYC/DDK-tagged | +Inquiry |
Cd74-1157M | Recombinant Mouse Cd74 Protein, His-tagged | +Inquiry |
CD74-920R | Recombinant Rat CD74 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD74-170H | Recombinant Human CD74 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CD74-2603HCL | Recombinant Human CD74 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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