Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Antibody > Monoclonal Antibodies > Mouse Anti-Human CD8A Monoclonal Antibody

Mouse Anti-Human CD8A Monoclonal Antibody

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Mouse(9)
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By Tag
Fc-His(1)
GST(1)
His(8)
N/A(1)
Cat. No.:
CABTT-003MH
ProductOverview:
Mouse monoclonal antibody to Human CD8A.
Antigen Description:
The OKT8 monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 αβ) or as a homodimer (CD8 αα). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T-cell development and activation of mature T cells. Preliminary testing indicates that OKT8 and two other mouse anti-human CD8 antibodies (clone RPA-T8, Cat. No.14-0088 and clone HIT8a, Cat. No.14-0089) do not compete with each other for binding to human peripheral blood leukocytes by flow cytometric analysis, suggesting that they do not bind to similar epitopes or block each other by steric hindrance.
Clone:
PLU9
Host animal:
Mouse
CrossReactivity:
Human
Isotype:
IgG2a
Concentration:
0.5 mg/ml
Application:
FCM
Form:
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Tag:
Purified
Storage:
Store at 2‐8°C
nullValue_other:
FunctionMHC class I protein binding; coreceptor activity; protein binding; protein homodimerization activity; protein kinase binding


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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