Recombinant Human Small Nuclear Ribonucleoprotein D3 Polypeptide 18kDa, His-tagged

• Cat.No.: SNRPD3-6878H
• Product Overview: Recombinant human SNRPD3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. MW: 16.0 kDa.

Specification

• Description: SNRPD3 is a small nuclear ribonucleoprotein (snRNPs) that comprises the spliceosome in eukaryotes. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol 0.5M NaCl, 2mM DTT, 0.1mM PMSF.
• Molecular Mass: 16.0 kDa (146aa), confirmed by MALDI-TOF.
• Protein length: 1-126aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MSIGVPIKVL HEAEGHIVTC ETNTGEVYRG KLIEAEDNMN CQMSNITVTY RDGRVAQLEQ VYIRGSKIRF LILPDMLKNA PMLKSMKNKN QGSGAGRGKA AILKAQVAAR GRGRGMGRGN IFQKRR
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa [ Homo sapiens ]
• Official Symbol: SNRPD3
• Synonyms: SNRPD3; small nuclear ribonucleoprotein D3 polypeptide 18kDa; SMD3; Sm-D3; small nuclear ribonucleoprotein Sm D3; snRNP core protein D3; small nuclear ribonucleoprotein polypeptide D3; small nuclear ribonucleoprotein D3 polypeptide (18kD)
• Gene ID: 6634
• mRNA Refseq: NM_004175
• Protein Refseq: NP_004166
• MIM: 601062
• UniProt ID: P62318
• Chromosome Location: 22q11.23
• Pathway: Sm core complex, organism-specific biosystem; Spliceosome, U1-snRNP, organism-specific biosystem; mRNA Splicing, organism-specific biosystem; snRNP Assembly, organism-specific biosystem
• Function: enzyme binding; histone pre-mRNA DCP binding; protein binding