Recombinant Human Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor, Alpha, His-tagged
Cat.No. : | NFKBIA-6897H |
Product Overview : | Recombinant human NFKBIA protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 37.7 kDa. |
- Specification
- Gene Information
- Related Products
Description : | NFKBIA is members of the IkB family of proteins can be divided into four groups (IkB-alpha, IkB-beta, IkB-gamma, IkB-epsilon). NFKBIA inhibits the NFkB complex by binding and sequestering it in the cytoplasm. Upon stimulation, NFKBIA is phosphorylated on serine residues marking it for degradation by the ubiquitin pathway. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl. |
Molecular Mass : | 37.7 kDa (337aa), confirmed by MALDI-TOF |
Protein length : | 1-317aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MFQAAERPQE WA MEGPRDGL KKERLLDDRH DSGLDSMKDE EYEQMVKELQ EIRLEPQEVP RGSEPWKQQL TEDGDSFLHL AIIHEEKALT MEVIRQVKGD LAFLNFQNNL QQTPLHLAVI TNQPEIAEAL LGAGCDPELR DFRGNTPLHL ACEQGCLASV GVLTQSCTTP HLHSILKATN YNGHTCLHLA SI HGYLGIVE LLVSLGADVN AQEPCNGRTA LHLAVDLQNP DLVSLLLKCG ADVNRVTYQG YSPYQLTWGR PSTRIQQQLG QLTLENLQML PESEDEESYD TESEFTEFTE DELPYDDCVF GGQRLTL |
Purity : | >90% by SDS-PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha [ Homo sapiens ] |
Official Symbol : | NFKBIA |
Synonyms : | NFKBIA; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; NFKBI; NF-kappa-B inhibitor alpha; IkappaBalpha; IKBA; MAD 3; ikB-alpha; I-kappa-B-alpha; nuclear factor of kappa light chain gene enhancer in B-cells; major histocompatibility complex enhancer-binding protein MAD3; MAD-3; |
Gene ID : | 4792 |
mRNA Refseq : | NM_020529 |
Protein Refseq : | NP_065390 |
MIM : | 164008 |
UniProt ID : | P25963 |
Chromosome Location : | 14q13 |
Pathway : | Activated TLR4 signalling, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; |
Function : | NF-kappaB binding; NF-kappaB binding; enzyme binding; heat shock protein binding; identical protein binding; nuclear localization sequence binding; protein binding; transcription factor binding; ubiquitin protein ligase binding; |
Products Types
◆ Recombinant Protein | ||
NFKBIA-6039M | Recombinant Mouse NFKBIA Protein, His (Fc)-Avi-tagged | +Inquiry |
NFKBIA-3340H | Recombinant Human NFKBIA protein(Phe2-Leu317), His-tagged | +Inquiry |
NFKBIA-819H | Recombinant Human NFKBIA Protein, MYC/DDK-tagged | +Inquiry |
NFKBIA-3634R | Recombinant Rat NFKBIA Protein, His (Fc)-Avi-tagged | +Inquiry |
Nfkbia-4398M | Recombinant Mouse Nfkbia Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
NFKBIA-437HCL | Recombinant Human NFKBIA lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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